Ecologie microbienne

Pneumococcal hydrogen peroxide production is associated with epithelial and pulmonary immune responses during pneumonia

Abstract Background Streptococcus pneumoniae (Spn) produces substantial amounts of hydrogen peroxide (H₂O₂), a metabolic byproduct with cytotoxic and immunomodulatory effects. Although pneumococcal H₂O₂ has been implicated in pathogenesis, its contribution to pulmonary immune res...

Clinical and ecological significance of bacterial dormancy in human pathogens

SUMMARY Bacteria can enter a transient state of reduced metabolic activity to survive temporary unfavorable conditions. This phenomenon, sometimes referred to as dormancy, growth arrest, or quiescence, enables pathogen survival inside and outside of their host, with major clinica...

Honeydew microbial ecology: A neglected frontier in multitrophic networks

Abstract Honeydew, the sugary excretion produced by sap-feeding Hemiptera, is one of the most common carbohydrate resources in many plant-based food webs. Honeydew supports a wide range of organisms, including ants, pollinators, (hyper-)parasitoids wasps, predatory insects, and m...

Aggregicoccus is a myxobacterial genus inherently deficient in fruiting genes

ABSTRACT Myxobacteria are fascinating and important prokaryotes with remarkable multicellular behaviors, which make them a model system for studying prokaryotic development and cooperation. Although there have been sporadic discoveries of myxobacterial species unable to fruit, it...

High-throughput protocol for assessing antibiotic resistance using agar dilution, acoustic liquid handling, and semi-automated image analysis

Conventional minimum inhibitory concentration (MIC) assays used to determine the antibiotic susceptibility of microorganisms are inherently low-throughput and labor intensive. Here, we present a high-throughput agar dilution MIC assay to efficiently assess resistance profiles acr...

Longitudinal gut microbiome dynamics in neurosurgical ICU patients: Enterococcus expansion as a feature of microbial restructuring

Abstract Background Gut microbiota alterations are commonly observed in critical illness, but their temporal dynamics in neurosurgical ICU patients remain insufficiently characterized. This study aimed to describe postoperative microbial trajectories and their clinical context du...

Genomic catalogue of giant viruses reveals expanded diversity and functional potential

Nucleocytoplasmic large DNA and Mirusviricota viruses exhibit taxonomic richness which continually expands due to metagenomic sequencing. Here we curate a database of giant virus metagenome-assembled genomes (GVMAGs V2), comprising 8,508 species-level representatives from 18,727...