École Normale Supérieure - PSL

Weak-Strong Uniqueness for the Landau Equation by a Relative Entropy Method

Abstract. We derive a weak-strong uniqueness and stability principle for the Landau equation in the soft potentials case (including Coulomb interactions). The distance between two solutions is measured by their relative entropy, which to our knowledge was never used before in sta...

On destructive memories and the role of language in living with one’s past

Abstract In the context of memory, the present paper investigates the consequences of undergoing a change concerning one’s ethical outlook. First, we motivate the idea that we can become alienated from our own memories by revisiting Bernard Williams’ idea of Relativism of distanc...

The Development of Compositionality in Language and Thought

Compositionality is the property of a representational system whereby complex meanings arise from the combination of simpler meaningful elements. Here we take a developmental perspective to understand the origins of compositional representational systems and their relation to lan...

Holographic two-point functions of heavy operators revisited

A bstract In this paper we investigate the holographic computation of the two-point functions of $$\frac{1}{2}$$ -BPS chiral primary operators with scaling dimensions ∆ ~ N or ∆ ~ N 2 in 𝒩 = 4 SU ( N ) SYM using Type IIB supergravity. First we consider giant graviton operators, r...

A barycenter-based approach for the multi-model ensembling of subseasonal forecasts

Abstract. Ensemble forecasts and their combination are examined from the perspective of probability spaces. By treating ensemble forecasts as discrete probability distributions, multi-model ensemble (MME) forecasts are reformulated as barycenters of these distributions. We consid...

Uneven TCR chain pairing constraints govern epitope recognition

Combinatorial pairing of independently recombined T cell receptor (TCR) α- and β-chains is central to diversifying the TCR repertoire. Although sequence motifs in one chain correlate with epitope recognition, the extent to which a single chain dictates specificity remains unclear...

Longitudinal evidence for decreasing statistical learning abilities across childhood

Abstract Statistical learning enables us to identify patterns in our environment and predict future events, thereby supporting a range of motor, cognitive, and linguistic skills. Despite its significance, the developmental trajectory of statistical learning has remained unclear d...

Robust inference and correlates from genetic associations with personality

Personality traits describe stable differences in how people think, feel and behave, and how they interact with and experience their social and physical environments1,2. Many questions remain unanswered about associations between DNA and personality traits, such as their robustne...

Contribution of mechanical forces in multiciliated cell differentiation

Abstract Multiciliated cells, through the coordinated beating of motile cilia, are vital for moving fluids in the brain and mucus in the airways and in the reproductive organs. Their dysfunction leads to diseases, associated with chronic airway infections, subfertility and ventri...

Caractères ostéologiques furileusauriens chez Genusaurus sisteronis Accarie et al., 1995,dinosaure abelisauridé de l’Albien (Crétacé inférieur) du Sud-Est de la France

International audience

Covalently Linked Peptides and Membrane Potential Enable CyaA Segment Translocation

The adenylate cyclase toxin (CyaA) from Bordetella pertussis intoxicates host cells by directly translocating its N-terminal catalytic domain across the plasma membrane; however, the forces driving this unique process remain poorly defined. Here, we dissect the membrane transloca...

Critical neuronal avalanches arise from excitation-inhibition balanced spontaneous activity

Neuronal avalanches are sequences of neural activations exhibiting scale-invariant statistics, indicative of critical dynamics. Theoretical studies proposed that the balance between excitation (E) and inhibition (I), along with neuromodulation, are key factors influencing this cr...

Questioning the Evidence for Host-Symbiont Codiversification in Mycorrhizal Symbioses

Abstract The vast majority of plants form mycorrhizal symbioses. The ecological importance of these mutualistic interactions has sparked interest in their long evolutionary history. By examining interaction networks and phylogenetic trees, several studies have suggested that plan...

Thermohaline gradients and frontal regimes in the northwestern Tropical Atlantic

Abstract. At the edge of the Amazon River plume, stirring by the North Brazil Current (NBC) and its eddies creates sharp surface thermohaline gradients on scales of O(1–100) km. This study provides a comprehensive picture of these gradients and fronts associated with the region's...

Topologically Engineered DNA Origami: Responsive Locking of DNA Quadrilateral for Biosensing Application

Abstract DNA nanotechnology offers unique opportunities for creating various accurate and responsive nanostructures. Nevertheless, large-scale conformational changes with high geometric precision and efficiency remain major challenges. Herein we report a topologically engineered...