Eastern Virginia Medical School

Plasma Phosphorylated Tau 217 Percentage by Race and Ethnicity in Preclinical Alzheimer Disease

Importance In trials targeting preclinical Alzheimer disease (AD), defined as amyloid pathology without cognitive symptoms, racial and ethnic differences in plasma phosphorylated tau 217 percentage (%p-tau217) may influence screening eligibility. Objective To characterize racial...

Return to Baseball Following Hip Arthroscopy for Femoroacetabular Impingement is a Home Run

Objectives: Because of the focus on throwing in baseball, a high volume of research has been dedicated to upper extremity injuries; however, research has suggested that approximately 30% of all injuries in professional baseball involve the lower extremity. Within that cohort, pla...

Simulation-Based Cesarean Education Improves Preclinical Knowledge and Comfort

Introduction: Cesarean delivery is the most common surgical procedure in obstetrics, yet preclinical medical students have limited exposure prior to clerkships. Procedural unfamiliarity may contribute to anxiety and decreased confidence during clinical training. Simulation-based...

Frequency-Specific Filtering Improves Speech Reception and Exam Grades in Low-Performing Female College Students

In low-performing female college students, frequency-specific filtering improved auditory processing in a controlled laboratory test and in class grades after recorded lectures. In a first test of efficacy, 76 listeners responded to a prerecorded command “Ready Charlie, go to [co...

Ovarian Microvascular Endothelial Cell Migration Is Dysregulated in PMOS

The objective of this study is to investigate whether ovarian microvascular endothelial cells (OMECs) from women with polyendocrine metabolic ovarian syndrome (PMOMECs) exhibit altered angiogenic responses compared with cells from healthy oocyte donors (HOMECs). This is a laborat...

Performance and safety of a multi-cancer early detection test: the PATHFINDER 2 study

Abstract Early cancer detection improves survival; however, most cancer types do not have guideline-recommended screening. We previously reported the first PATHFINDER study that established feasibility of cancer screening with a blood-based multi-cancer early detection (MCED) tes...

Type 2-low Asthma: Epidemiology, Multiomics, and Emerging Therapies

Abstract Purpose of Review Type 2-low (T2-low) asthma, characterized by low blood and sputum eosinophils and low fractional exhaled nitric oxide (FeNO), remains a major unmet need because of frequent corticosteroid insensitivity and a lack of targeted therapies. This review summa...

Patterns of sleep duration, quality, and midpoint across pregnancy in a longitudinal cohort study

Abstract Background Sleep health is a critical component of maternal well-being, and poor sleep during pregnancy is associated with adverse maternal-fetal and cardiometabolic outcomes. Although sleep across pregnancy has been examined in several longitudinal studies, fewer studie...

Rhinosinusitis in Adults Receiving Tumor Necrosis Factor Alpha Inhibitors and Anti‐CD20 Therapy: A Scoping Review

ABSTRACT Introduction Immunomodulatory therapies, including tumor necrosis factor alpha (TNF‐α) inhibitors and anti‐CD20 agents, are often used for autoimmune, inflammatory, and neoplastic disorders. While infection risk is well recognized, their association with rhinosinusitis r...

The Cardiac “Flip” Sign: A Simple Sonographic Marker for “Mirror Image Configuration” of the Great Arteries

ABSTRACT We hereby describe a new sonographic sign, the cardiac “flip” sign, to help in the prenatal detection of a right sided aortic arch with a right sided ductus arteriosus. This sign depends on pattern recognition where the sonologist/sonographer needs to obtain a cardiac sw...

A memorial tribute to Dr. Asgerally T. Fazleabas

Gregory W Burns, Yong Song, J Julie Kim; A memorial tribute to Dr. Asgerally T. Fazleabas, Biology of Reproduction, , ioag180, https://doi.org/10.1093/biol

Outcomes of Aseptic, Septic, and Occult Infected Index Nonunion Repair: A Retrospective Comparative Study

OBJECTIVES: To compare nonunion surgery effectiveness for occult infected, aseptic, and septic nonunions in patients identified using the FRI criteria. METHODS: Design: Retrospective Review Setting: Single Level I Tertiary Academic Center Patients Selection Criteria: All skeletal...

Cervicovaginal zinc and copper profiles across vaginitis phenotypes and hydrogel assignment: an exploratory pilot study

Abstract Zinc (Zn) and copper (Cu) support epithelial integrity, nutritional immunity, and host–microbiome interactions, yet cervicovaginal trace-metal dynamics across vaginitis phenotypes remain poorly defined. We prospectively quantified cervicovaginal lavage (CVL) Zn and Cu by...

Impact of MRI-to-surgery interval on pathological upstaging after robot-assisted radical prostatectomy: a real-world cohort study

Multiparametric MRI (mpMRI) is widely used for preoperative staging and surgical planning in prostate cancer. However, discrepancies between radiological and pathological staging are common. We evaluated staging concordance and investigated whether the interval between mpMRI and...