Drexel University

Policy Window as a Trapdoor: Rethinking the Multiple Streams Framework through the Defunding of U.S. Public Media

This article analyses the 2025 defunding of U.S. public media as a critical case to revisit Kingdon’s multiple streams framework (MSF). While MSF offers a useful heuristic for understanding policy change through the convergence of problem, policy, and political streams, its expla...

Role of small intestinal bacteria overgrowth in irritable bowel syndrome and anxiety: a retrospective Electronic Health Record (EHR)- based cohort study using triNetX

Abstract Aims : The goal of this study is to examine the relationship between small bacterial overgrowth (SIBO) and irritable bowel syndrome (IBS) with their subsequent risk of developing generalized anxiety disorder (GAD). Methodology : Data for this retrospective study was obta...

Vinyl Functionalization of Ti3C2T x MXene Enables Grafting of Sulfonated Polyelectrolytes for High Salt Rejection in Forward Osmosis Desalination

MXene membranes are promising for aqueous separations but are fundamentally limited by swelling-induced loss of selectivity and structural instability. Here, we report, for the first time, vinyl functionalization of Ti3C2Tx MXene nanosheets, which enables subsequent grafting of a...

Recent advances in etiology and treatment of von Hippel-Lindau Disease (VHLD)

Abstract Von Hippel-Lindau disease (VHLD) is a rare autosomal dominant disease, occuring in ~ 1 in 35,000 individuals. Overall, individuals with inherited mutations in the VHL tumor suppressor gene are predisposed to a variety of cancer, including high frequencies of clear cell r...

Characterization of Anticholinergic Medication Use and Its Associations With Everyday Memory Problems and Cognitive Decline in Autistic Adults With Higher Support Needs

ABSTRACT Among older adults in the general population, medications with anticholinergic (AC) effects are associated with declines in cognitive functioning and with dementia and Alzheimer's disease. Autistic people have high rates of co‐occurring medical conditions and polypharmac...

Impact of timing on outcomes following redo-sternotomy after initial CABG or valvular surgery

The optimal timing of reoperation for those who need repeat coronary artery bypass grafting (CABG) and valve surgery is not well established. Early re-entries may be technically challenging due to adhesions and incomplete healing, while delayed interventions may expose patients t...

Extreme Risk Protection Order laws and fatal violence against women: a quasi-experimental study

Background Rates of intimate partner homicides of women in the USA are high relative to other high-income countries, especially those involving firearms. We evaluated one potential policy solution by examining state Extreme Risk Protection Order (ERPO) firearm transfer laws and i...

Oropharyngeal Lateral Wall Collapse as a Predictor of Hypoglossal Nerve Stimulation Response: A Systematic Review and Meta-Analysis

Purpose Oropharyngeal lateral wall collapse (OPLW) on drug-induced sleep endoscopy (DISE) may influence outcomes after hypoglossal nerve stimulation (HNS) for obstructive sleep apnea (OSA). This systematic review and meta-analysis evaluates whether DISE-defined OPLW collapse is a...

Human spinal interneurons repair the injured rat spinal cord through synaptic integration

Spinal cord injury (SCI) results in irreversible disruption of motor, sensory, and autonomic circuits with no approved reparative treatment to restore lost function. Endogenous V2a spinal interneurons (SpINs) have been implicated as a key component in recovery post-SCI, but the i...

Delayed methotrexate toxicity after initial clearance in a critically ill patient with severe fluid overload

Methotrexate (MTX) toxicity is a life-threatening complication in oncology patients. We report a 19-year-old male with newly diagnosed Burkitt lymphoma who received high-dose methotrexate as part of induction chemotherapy and initially met protocol-defined serum clearance criteri...