Dr. Vitthalrao Vikhe Patil Foundation’s Medical College

Indigenous enFnCas9 and TnpB-Based CRISPR Technology: Translational Applications in India

AbstractCRISPR-based genome-editing technologies are progressing rapidly, outperforming conventionalCRISPR-Cas9 methods in medicinal and biotechnological applications. With unique structural andtranslational advantages, transposon-associated TnpB-based OMEGA systems and engineere...

Circulating microRNAs: a new era in early detection of oral squamous cell carcinoma (OSCC) — a systematic review and meta-analysis

BACKGROUND: The chances of oral squamous cell carcinoma (OSCC) being diagnosed at an early stage are very low, and this leads to a poor prognosis. The presence of circulating miRNAs (miRNAs) in blood or saliva is now a potential non-invasive diagnostic biomarker, although the dia...

Multi-source energy management in electric vehicles: Performance analysis using metaheuristic optimization strategies

Hybrid energy storage systems (HESS) are considered as the optimal energy source for electric vehicles (EVs). Indeed, optimizing energy management efficiency and enhancing system lifespan are vital to improving the sustainability and reliability of EVs. However, the high charging...

Plant-mediated synthesis of silver nanoparticles via Dolichandrone falcata extract with their antimicrobial and anticancer efficacy

This research explores the green synthesis of Ag NPs using the Dolichandrone falcata leaf extract and evaluates their antifungal, antibacterial, and anticancer efficacy. SEM and TEM characterization showed spherical particles with a mean diameter of 71.3 ± 10 nm. The biosynthesiz...