Dr. D.Y. Patil Vidyapeeth, Pune

Methodological limitations in evaluating dietary pattern analysis and calcaneal bone quality in a paediatric cohort: a commentary

This commentary aims to discuss the article by Liu et al., “Association between dietary patterns and bone health among children and adolescents: a cross-sectional study.” This study describes the association between dietary patterns and bone health in Chinese children and adolesc...

Adjunctive antimicrobial photodynamic therapy in the nonsurgical treatment of periodontitis: an umbrella review

Antimicrobial photodynamic therapy (aPDT) has been proposed as a locally acting adjunct to subgingival instrumentation for periodontitis. This umbrella review aimed to synthesize and critically appraise systematic reviews of adjunctive aPDT during active nonsurgical periodontal t...

Bridging Conventional and Natural Therapies for Recurrent Aphthous Stomatitis: A Systematic Review and Meta-Analysis of Triamcinolone and Non-Steroidal Alternatives

Background: Recurrent aphthous stomatitis (RAS) is a chronic inflammatory condition that causes painful oral ulcers that impair eating and speech. Topical triamcinolone is commonly used, but non-steroidal natural and synthetic alternatives are increasingly studied. This systemati...

Current Evidence on Gene-Based and Epigenetic Therapeutic, Diagnostic, and Prognostic Strategies in Epithelial-Derived Carcinomas: A Scoping Review

Background: Epithelial-derived carcinomas exhibit genomic instability due to genetic mutation and epigenetic dysregulation. Mechanisms such as DNA methylation, histone modifications, and noncoding RNA regulation may lead to tumor progression, immune evasion, and treatment resista...

Laparoscopic Total Hysterectomy with Bilateral Salpingectomy in a Perimenopausal Woman with Chronic Cervicitis and Pelvic Adhesions

Abstract Chronic cervicitis is a common gynecological condition that may present with persistent vaginal discharge and pelvic discomfort. When conservative management fails, surgical intervention may be warranted. We report the case of a 42-year-old perimenopausal woman with chro...

Correlation of Serological Status with Disease Activity Score 28-Erythrocyte Sedimentation Rate Score in Elderly Patients with Rheumatoid Arthritis: A Cross-sectional Study

Abstract Background: Rheumatoid arthritis (RA) in the elderly is a clinically distinct entity with unique presenting features, serological profiles, and high disease burden. Elderly-onset RA (EORA), defined as RA with onset at or after 65 years, remains understudied in the Indian...

Zirconium Dioxide Nanoparticles in Bone Tissue Engineering: Recent Advances, Biological Interactions, and Future Perspectives

Bone defects from trauma, tumor resection, infection, and degenerative disease remain a large clinical problem, and the grafting strategies used to treat them still carry familiar limitations: donor-site morbidity for autografts, variable integration and supply constraints for al...

Emerging Biomarkers Across the Clinical Spectrum of SARS-CoV-2 Infection and Long COVID

Long COVID, also referred to in the literature as postacute sequelae of SARS-CoV-2 infection (PASC) or postacute COVID-19 syndrome (PACS), is a chronic and heterogeneous multisystem condition persisting beyond acute COVID-19. For consistency, this review uses the term “Long COVID...

Generational changes in lung function in adults from several world regions: results from the Burden of Obstructive Lung Disease study

This study estimated birth cohort effects on lung function using BOLD (Burden of Obstructive Lung Disease) data from 28 569 adults born between 1902 and 1976 across 41 sites in 34 countries. Forced vital capacity (FVC), forced expiratory volume in 1 s (FEV 1 ) and the FEV 1 /FVC...

Parental Stress in the Pediatric Intensive Care Unit and Its Association with Clinical Outcomes: A Prospective Observational Study

Abstract Background: Children, who represent the emotional center of parents and the future of the nation, when hospitalized in the pediatric intensive care unit (PICU), place caregivers under substantial psychological strain due to disruption of family life and persistent uncert...

A field-acquired annotated dataset for robust and generalizable pomegranate disease detection using generative learning

Pomegranates are popular in India for their health benefits and high levels of antioxidants and vitamins. Detecting diseases in pomegranates is important for maintaining their quality. However, inconsistent dataset annotations and challenging field conditions make it difficult to...

Emerging materials and technologies for next-generation sensors in smart IoT systems: a comprehensive review

As the Internet of Things (IoT) continues to advance at an unprecedented rate, there is a growing need for intelligent, adaptable, low-power and sustainable sensing platforms that can operate autonomously over long periods. This paper examines the technological advances in IoT se...

Thymidine kinase 1 is elevated in prostate cancer and correlates with tumor aggressiveness: a systematic review and meta-analysis

Non-invasive biomarkers can inform prostate cancer diagnosis, surgical decision-making, and treatment. However, early screening biomarkers, including prostate-specific antigen (PSA), lack specificity due to elevation in benign conditions. Thymidine kinase 1 (TK1), a DNA synthesis...

Diagnostic Accuracy of ChatGPT Plus (GPT-4o) for the Interpretation of Chest and Extremity Radiographs Against Routine Radiologist Reporting: A Single-Centre, Retrospective, Cross-Sectional Study

Abstract Multimodal large language models are now widely accessible, but their diagnostic capability on plain-film radiographs is poorly characterized. Most evaluations in radiology address purpose-built convolutional networks rather than general-purpose conversational assistants...

Effect of chocolate preference and cocoa content on experimentally induced muscle pain

Abstract Objectives Chocolate consumption has been associated with pain reduction, but it remains unclear whether this effect depends on cocoa concentration or individual preference. This study aimed to investigate whether chocolate preference and/or cocoa content modulate experi...

A next-generation hybrid generative learning framework integrating dual GAN and Swin Transformer–CNN for robust early diagnosis of pomegranate diseases

Nowadays, health is the most important thing, and everything is hybrid, so we need to take care of our health, which is our first priority. To identify pomegranate diseases and determine whether a pomegranate is healthy or dis-eased, this research proposes a novel hybrid method t...

Resilience and Disparity: A statistical reevaluation of the pandemic-era self-harm crisis using Global Burden of Disease data (1990–2023)

Background Early models projected pandemic-driven increases in suicide and violence. This study utilizes Global Burden of Disease (GBD) 2023 data to evaluate mortality trajectories for self-harm and interpersonal violence (1990-2023), assessing regional and demographic pandemic-e...

As India expands HPV vaccination for girls, inclusion of boys deserves consideration

Human Papilloma Virus (HPV) infection is Commonly associated with cervical carcinoma; however, HPV affects both female and male and contributes to a broad spectrum of diseases. HPV infection can cause benign conditions such as genital warts as well as HPV-associated malignancies,...

Age Cohort Patterns of Socioeconomic Inequalities in High-Risk Body Mass Index (BMI) and Waist to Hip Ratio (WHR) Composite: Findings from Nationally Representative Survey

<title>Abstract</title> Background Obesity is a growing global health challenge, with central adiposity posing particularly high cardiometabolic risk. In low- and middle-income countries (LMICs) like India, the coexistence of undernutrition and obesity reflects a double burden of...

Implant-Supported and Conventional Dentures: A Meta-Analysis in Older Adults

Statement of problem Edentulism is highly prevalent among older adults, with approximately 30% of adults aged ≥60 years affected by complete tooth loss in at least one dental arch. Conventional complete dentures (CCDs) often provide suboptimal retention and stability, negatively...