Cliniques Universitaires Saint-Luc

Oligogenic inheritance in epilepsy: A systematic exome‐wide analysis

Abstract Objective Genetic factors contribute to the majority of epilepsies, but the exact genetic cause remains unknown in most patients. Incomplete penetrance and variable expressivity are frequent, and recent studies showed a burden of deleterious variants in epilepsy genes, s...

Vancomycin optimised dosing regimens for critically ill patients receiving renal replacement therapy

Optimal dosing of vancomycin in critically ill patients receiving renal replacement therapy (RRT) is uncertain due to high pharmacokinetic variability. We aimed to develop individualised vancomycin dosing recommendations that optimise efficacy while minimising toxicity. Prospecti...

Scala Tympani Versus Scala Vestibuli Cochlear Implantation in Incomplete Partition Type III Malformation

Incomplete partition type III (IP-III) is a congenital inner ear malformation characterized by a deficient separation between the cochlear modiolus and the internal auditory canal (IAC). In patients with IP-III and severe-to-profound sensorineural hearing loss, cochlear implantat...