Clinical Emergency Hospital Bucharest

Minimalist Footwear and Knee Joint Loading During Walking in Healthy Adults: A Systematic Review of Evidence for Osteoarthritis Prevention

Background/Objectives: Minimalist footwear has been proposed as a passive means of reducing knee loading, but its effects during walking in healthy adults, the population relevant to primary prevention of knee osteoarthritis (KOA), have not previously been synthesized. Methods: F...

Malignancies in horseshoe kidneys: an updated review

Out of over 4000 available studies about horseshoe kidney (HSK), we selected 89 representative articles that emphasized the most common genetic lesions and tumors that can occur in these patients. Renal cell carcinomas, carcinomas of the urothelial tract, and Wilms tumor are the...

Integrating Artificial Intelligence into Orthopedic Practice: Modeling Attitudes and Intentions to Use AI

Background/Objectives: Artificial intelligence is increasingly used in medicine, particularly in orthopedics, to support medical image interpretation, diagnosis, clinical decision-making, and treatment selection. Its integration into clinical practice depends largely on doctors’...

Admission Liver Injury Is an Independent Predictor of Early and Overall Mortality in Hospitalized Patients with Moderate-to-Critical COVID-19: A Retrospective Cohort Study

Background: Liver injury (LI) is frequently observed in patients with COVID-19, particularly in severe forms of disease. However, its prognostic significance remains incompletely defined. Aim: To evaluate the association between LI at admission and clinical outcomes in hospitaliz...

Sex-Related Differences in Clinical Characteristics and Outcomes Among Patients Clinically Managed for Suspected Bacterial Infection in the Emergency Department

Background and Objectives: Suspected bacterial infection is one of the leading presentations to the Emergency Department (ED) and is still associated with considerable morbidity and mortality. There is increasing evidence that biological sex may influence host immune responses, d...

Intraoperative Displacement of a Pterygoid Implant into the Pterygopalatine Fossa and Its Surgical Retrieval: A Case Report

Background/Objectives: Pterygoid implants are increasingly used to provide distal support in full-arch maxillary rehabilitation, improving biomechanical stability and reducing posterior cantilevers. Despite high reported survival rates, their placement is technically demanding be...

Cardiovascular–Kidney–Metabolic Syndrome and Its Hepatic Dimension: A Narrative Review

Metabolic syndrome came to the attention of the scientific community several decades ago, and its definition has undergone multiple changes over time. It is currently defined by the coexistence of hypertension, central obesity, dyslipidemia, and impaired glucose metabolism, with...

Molecular profiling of thalassemia in Southeastern Romania

Abstract Background Thalassemias represent a major group of hereditary hemoglobin disorders with significant global health impact, yet molecular data from Eastern European populations, particularly from Romania, remain limited. Purpose This study was aimed at comprehensively char...

Epidemiological Assessment of Oral and Oropharyngeal Squamous Cell Carcinomas Before, During, and After the COVID-19 Pandemic, 2018–2024

Background/Objectives: Evidence regarding changes in oral and oropharyngeal squamous cell carcinoma (SCC) care across the COVID-19 pandemic remains limited, particularly in Eastern Europe. This study evaluated temporal changes in surgical admission volume, operative complexity, a...

Reactive Blue 21 Dye Degradation and Surface Modification of Cu and Ag/Cu Thin Films Prepared by Pulsed Laser Deposition

In the present work, the potential applications of Cu thin films and Ag/Cu bilayer thin films obtained by the pulsed laser deposition (PLD) technique are investigated in terms of the physicochemical effects resulting from their interaction with an aqueous solution containing Reac...

Minimally Invasive Fassier–Duval Telescopic Rodding of the Lower Limb in Pediatric Osteogenesis Imperfecta: Current Evidence and Implications for Type I (Non-Deforming) Disease

Osteogenesis imperfecta (OI) is the most common heritable bone-fragility disorder, with type I (non-deforming OI) representing its mildest classical phenotype (historically referred to as Lobstein disease). Intramedullary (IM) rodding is essential for managing recurrent long-bone...

Revisiting gallbladder stones structure through integrated multiscale physicochemical characterization

Gallstones are complex biominerals formed through physicochemical, metabolic, and microbial processes. In this study, gallstones were comprehensively characterized, revealing a complex elemental profile comprising C, N, O, Mg, Al, Si, P, S, Ca, Cu, Mn, Fe, Co, Zn, and Cd. The cha...

Bioactive Multilayer Poly(ε-caprolactone)–Chitosan Coatings for Spinal Screws

Spinal surgery involves highly complex procedures where the risk of severe complications, including postoperative infections, may compromise both surgical success and patient survival. In this study, functional coatings for spinal screws were developed to promote bone integration...

Predictive Factors for Acute and Late Genitourinary and Gastrointestinal Toxicity Following Modern Radiotherapy for Prostate Cancer: A Narrative Review of Clinical, Dosimetric, Immunological, and Genetic Determinants

Background: Despite advances in prostate cancer (PC) radiotherapy, including intensity-modulated radiotherapy (IMRT), volumetric modulated arc therapy (VMAT), and stereotactic body radiotherapy (SBRT), genitourinary (GU) and gastrointestinal (GI) toxicities remain important compl...

Improving nurses' compliance with evidence-based falls prevention practices in urology settings: a best practice implementation project.

INTRODUCTION: Falls represent multifactorial adverse events and are a major challenge in the care of patients with urological conditions. AIM: The aim of this evidence implementation project was to improve fall prevention practices in three urology wards of a specialized hospital...

Mood Disorder Symptoms Among Medical Doctors in Romania: Prevalence and Associations with Suicide Risk and Quality of Life

Mood disorder symptoms represent an important but understudied mental health concern among physicians in Romania, with potential implications for quality of life and suicide risk. This cross-sectional study included 104 medical doctors. Validated self-report instruments were used...

Apparent diffusion coefficient metrics for adult-type diffuse gliomas classified according to WHO 2021: a systematic review

Abstract Purpose This study aimed to determine the associations of apparent diffusion coefficient (ADC) values with the molecular and histological subtypes of adult-type diffuse gliomas classified in accordance with the 2021 World Health Organization (WHO) Classification of Tumor...

Interventions to reduce diabetes-related distress among adults with type 1 and type 2 diabetes: protocol for a systematic review and meta-analysis

Diabetes distress (DD) refers to the emotional and psychological burden experienced by individuals living with diabetes. Randomized controlled trials (RCTs) have investigated the efficacy of interventions on DD among adults with type 1 diabetes or type 2 diabetes. We aimed to sys...

What Is Stressful About Medical Liability? A Retrospective Jurisprudential Analysis of Moral Damages and Discussions on Its Impact on Healthcare Professionals’ Well-Being

Background/Objectives: Medical liability litigation in Romania has risen steadily over the past decade, yet the quantification of moral (non-pecuniary) damages remains entirely at the discretion of each judge, with no standardized reference. This raises concerns about consistency...

Physicians Retain Moral Responsibility but Endorse Institutional Co-Responsibility in AI-Assisted Decisions: An Exploratory Vignette Study

Background: Artificial intelligence (AI) systems, including large language models, are increasingly used in clinical practice, whether consulted informally by clinicians or introduced by employers into decision workflows. It remains unclear how physicians attribute moral responsi...