City University of New York

Targeting Oncogenic KRAS Using Peptide Nucleic Acid Oligomers Attached to Cell-Penetrating Peptides

Approximately 30% of tumors contain an activating mutation in the oncogene KRAS, leading to increased cell proliferation that often promotes non-small cell lung cancers, colorectal adenocarcinomas, pancreatic ductal adenocarcinomas (PDAC), and other cancers. Among the most common...

Zippers and Twisters: Planes of Satellite Galaxies Emerge from Whirling and Shocking Gas Streams in the Cosmic Web

Abstract We investigate dwarf satellite systems around massive centrals analogs (Milky Way to Centaurus A) in the NewHorizon simulation. Using simple estimators limiting overdetection, we identify planes of satellites comparable to observations in 30%–70% of cases. The full sampl...

Emerging innovations in movement ecology to address planetary challenges

Abstract Movement ecology—the study of how and why animals move within their environments—stands to offer transformative insights into our rapidly changing world, with benefits for both nature and people. Here, we present the first global horizon scan for movement ecology, engagi...

Mid-infrared long-range surface polaritons in two-dimensional van der Waals materials

The discovery of graphene plasmons (GPs) and hyperbolic phonon polaritons (HPhPs) in two-dimensional (2D) van der Waals (vdW) materials has enabled extreme light confinement and enhanced light-matter interactions, holding the promise for miniaturized mid-infrared (mid-IR) photoni...

An Adult Presentation of KIF11 ‐Related MCLID Syndrome: Case Report and 40‐Year Follow‐Up

Pathogenic variants in KIF11 are linked to autosomal dominant syndromes with microcephaly, chorioretinopathy, lymphedema, and intellectual disability (MCLID), though adult presentations remain underreported. We report a 42-year-old female presenting with a de novo single-amino ac...