Cipher Gene (China)

The Exhausted Defence Phenotype: A Proposed Psychoneuroimmunoendocrine Subphenotype of Affective Deficiency, Organized Around Failed Nocturnal Autonomic Restoration

A recognizable group of patients presents with chronic myofascial pain, stiffness organized along defensive chains, non-restorative sleep, fatigue disproportionate to exertion, paraesthesiae, histamine-related symptoms and a diffuse sense of bodily unsafety, while standard invest...

The Exhausted Defence Phenotype: A Proposed Psychoneuroimmunoendocrine Subphenotype of Affective Deficiency, Organized Around Failed Nocturnal Autonomic Restoration

A recognizable group of patients presents with chronic myofascial pain, stiffness organized along defensive chains, non-restorative sleep, fatigue disproportionate to exertion, paraesthesiae, histamine-related symptoms and a diffuse sense of bodily unsafety, while standard invest...

From Affective Deficiency to Compensatory Overprotection: A Proposed Model of Parental Agency Substitution, Executive Undertraining, and Adult Functional Dependence

Overprotective parenting is commonly conceptualized as the opposite of neglect. This paper proposes, instead, that the two can coexist within a single developmental trajectory: a caregiver may be affectively insufficient in a child's earliest years and later become functionally e...