Chongqing Three Gorges Central Hospital

Yiqi Huoxue Compound promotes neuroprotection against ischemic stroke by inhibiting apoptosis through the activation of PI3K/AKT pathway

Yiqi Huoxue Compound (YQHX), a traditional Chinese medicine formulation, has demonstrated therapeutic potential for ischemic stroke (IS). However, its underlying mechanisms are not fully understood. This study aimed to elucidate the neuroprotective effects and mechanisms of YQHX...

A cfDNA fragmentomics-based liquid biopsy assay for early detection of oral cancer

Abstract Background Early detection of oral cancer improves outcomes, but remains limited by the invasiveness and low sensitivity of current screening methods. Methods This study included 342 participants (200 in the training and 142 in the validation cohorts). Plasma cfDNA under...