Children's Hospital of Philadelphia

Pre-trained knowledge transfer with application in multisystem inflammatory syndrome subphenotyping in children

Multisystem inflammatory syndrome in children (MIS-C) is a severe post-acute sequela of SARS-CoV-2 infection in children and presents with highly heterogeneous signs and symptoms. Disentangling the clinical manifestations of MIS-C by characterizing its subphenotypes can help iden...

Distraction in anterior plagiocephaly: technique, risks, and long-term results

PURPOSE: The purpose of this study is to define the perioperative outcomes and long-term aesthetic outcomes of patients with unicoronal craniosynostosis (UCS) treated with fronto-orbital distraction osteogenesis (FODO) and compare them to a contemporaneous cohort treated with con...

Community Firearm Violence, Youth Depression, and Suicide Risk in Philadelphia: 2017–2024

OBJECTIVES: Youth suicide and depression rates increased during the COVID-19 pandemic. In Philadelphia, firearm violence surged and has since declined to pre-pandemic levels. We examined whether youth depression and suicide risk also declined and whether community firearm violenc...

Exercise and Sport Participation in Pediatric Hypertrophic Cardiomyopathy: A Changing Paradigm

Abstract Purpose of Review This review aims to detail recent research and guidelines that have changed the approach to exercise and sport participation in the pediatric hypertrophic cardiomyopathy (HCM) population. Recent Findings Recent studies, including the landmark LIVE-HCM c...

Disparities in Medical Documentation for Pediatric Headache in the Emergency Department

OBJECTIVES: We examined associations between patients' socioeconomic and clinical factors and the thoroughness of clinical notes for children visiting the pediatric emergency department (ED) for headache. METHODS: This is a secondary analysis of data from a retrospective chart re...

Neonatal Point-of-Care Lung Ultrasonography: Techniques and Normal Findings

Point-of-care lung ultrasonography (POC-LUS) has become a routine bedside tool for evaluating respiratory status in many neonatal intensive care units. This article walks neonatologists through the fundamentals of its application-probe selection, system setup, and image acquisiti...