Changchun Institute of Applied Chemistry

Scalable Patterning of Organic Electrochemical Transistors for Logic Gates and Neuromorphic Computing

ABSTRACT Organic electrochemical transistors (OECTs) are promising building blocks for bioelectronics owing to their efficient ion–electron coupling, soft‐material compatibility and high transconductance. However, their large off‐state currents and poor scalability have so far li...

Reprogramming Sphingolipid Metabolic and Redox Homeostasis with an Injectable Botanicals/Nanozymes Hydrogel for Inhibiting Postoperative Recurrence and Metastasis in Breast Cancer

ABSTRACT Postoperative recurrence and metastasis in breast cancer remain major clinical challenges, primarily driven by persistent inflammation responses and secondary infections at surgical sites. These pathological processes trigger sphingolipid dysregulation and generate the r...

Sb3+-Sensitized Self-Trapped Exciton Emission and Energy Transfer for Tunable Tricolor and Near-White Luminescence in Cs2NaScCl6 Double Perovskite Microcrystals

Abstract Metal-ion doping in lead-free double perovskites is an effective strategy for tailoring lattice structures and enhancing photoluminescence. Herein, Sb3+/Mn2+/Tb3+ codoped Cs2NaScCl6 microcrystals with tunable blue-green-red tricolor emission were synthesized via a solvot...

Nanoscale Thermocatalysis: Mechanisms, Regulation, and Biomedical Applications

ABSTRACT Thermal‐driven catalysis has emerged as a promising interdisciplinary field that integrates thermal science, catalysis, nanotechnology, and biomedicine by utilizing thermal energy as a driving force for catalytic reactions. Unlike conventional catalytic systems, thermal‐...

Chirality-Induced One-Way Magnetoresistance in Gold Nanocrystals

Abstract Magnetoresistance (MR), a cornerstone for quantum materials and quantum devices, is usually symmetric (sometimes antisymmetric) under magnetic field reversal. Here, we report a chirality-induced one-way magnetoresistance (ChiMR) in gold nanocrystals, where MR is strongly...

Synergistic Dual‐Photoreaction Crosslinking Enables High Phosphoric Acid Retention in High‐Temperature Proton Exchange Membranes

ABSTRACT Phosphoric acid (PA)‐doped high‐temperature proton exchange membranes (HT‐PEMs) enable anhydrous proton conduction but remain limited by PA migration, excessive swelling, and conductivity decay. Here, anthracenylmethyl groups are introduced into PEEK side chains through...

In-Situ Synthesis of CuF2 Integrated Cathodes for High-Performance Lithium Metal Batteries with Superb Stability

Abstract Copper fluoride (CuF2) exhibits high theoretical specific capacity and an attractive redox potential, making it a promising lithium metal batteries (LMBs) cathode material. Nevertheless, its cycling performance remains inadequate, with severe capacity loss occurring over...

Integrating Cation Disordering With Surface Tailoring via Sn/In Co‐Doping for High‐Performance Perovskite Cathode

ABSTRACT The development of stable, durable cathodes with high oxygen reduction reaction (ORR) activity remains a critical challenge in solid oxide fuel cell (SOFC) research. This work employs a Sn‐In co‐doping strategy to synthesize a cathode material with the nominal compositio...

Mechanistic insights into HipA‐mediated bacterial persistence: Role of initial cellular states and toxin expression kinetics

Abstract Persistent bacteria subpopulations showing multidrug tolerance pose significant challenges to antibiotic therapy. While the HipBA toxin–antitoxin (TA) system is known to play a role in persister formation, existing studies predominantly focus on its kinase activity and i...

Modulating the Thermodynamics and Kinetics of Psychedelics at Serotonin Receptors via Terahertz Waves

Abstract Precise control over the thermodynamics and kinetics of receptor–ligand interactions is pivotal for manipulating physiological processes and developing targeted therapies. However, conventional pharmacological approaches often lack the spatiotemporal precision required f...

Dynamic Supramolecular Helicity in a Multi-Aluminum Porphyrin Catalyst Enables Stereocontrolled Synthesis of Ultrahigh-Molecular-Weight Isotactic Poly(propylene oxide)

Abstract Isotactic poly(propylene oxide) (iPPO) is a robust polyether with photodegradability. However, its stereoselective synthesis from racemic propylene oxide (rac-PO) remains dominated by preconfigured axially chiral cobalt/chromium bimetallic catalysts. Here, we report an i...

Lethal C57BL/6 mouse model for Yezo virus infection and antiviral therapeutic evaluation

Yezo virus (YEZV) is an emerging tick-borne orthonairovirus that causes febrile illness and hepatic injury in humans. However, its pathogenesis and effective antiviral interventions remain poorly characterized. In this study, we generated a lethal, mouse-adapted YEZV strain throu...

Ultrahigh-sensitivity adaptive solar-blind organic neuromorphic sensors for robust corona discharge monitoring

Abstract Low‑cost and high‑efficiency corona-discharge detection is essential for safe high‑voltage transmission operation, yet state‑of‑the‑art solar‑blind ultraviolet (SBUV) photodetectors for corona monitoring suffer from insufficient sensitivity, poor stability and weak anti‑...

Biodegradable Superabsorbent Polymer from CO2-Based Polycarbonate

Abstract Superabsorbent polymers (SAPs) are widely used but remain dominated by nondegradable poly(acrylic acid)-based networks, creating sustainability concerns. Natural polymer-based alternatives often require acrylic acid grafting to achieve high absorbency, compromising degra...

Immunomodulatory, Antibacterial, Antioxidative and EGF‐Delivering Hydrogel Remodels Wound Microenvironment for Infected Diabetic Wound Healing

ABSTRACT The treatment of diabetic wounds remains a major challenge due to persistent bacterial infections, chronic inflammation, and impaired angiogenesis. To address these issues, we develop an immunomodulatory and antibacterial hydrogel integrating epidermal growth factor (EGF...

A Chloroplast-Inspired Theranostic Nanoplatform for Self-Sustaining Oxygen-Elevating Photodynamic Therapy and Glutathione-Triggered Carbon-Centered Radical Synergistic Therapy

Achieving precise drug delivery to the tumor site can minimize systemic side effects caused by off-target effects. As a therapy that depends on oxygen content, photodynamic therapy (PDT) is significantly constrained by the hypoxic nature of the tumor microenvironment (TME). Compa...

Empowering PolymericMaterials Discovery by ArtificialIntelligence

Abstract Polymeric materials underpin modern technologies spanning energy storage, microelectronics, healthcare and sustainable manufacturing. Yet their rational design remains exceptionally challenging because material performance emerges from complex interactions among molecula...

An N-acetylated daropeptide modulates nematode development

The symbiotic bacterium Photorhabdus is a rich source of bioactive secondary metabolites that mediate tripartite interactions with nematodes and insect hosts. However, natural products of ribosomal origin remain largely underexplored within this ecological niche. Here, we report...