Center for Excellence in Brain Science and Intelligence Technology

High-frequency visual stimulation can increase medial temporal lobe ripple oscillation density

Abstract Background Flickering visual stimulation can evoke neural oscillations, which can influence ongoing brain activity. Electrophysiological recordings of neural oscillations in the ripple band (80–180 Hz) show that these high-frequency oscillations occur in the neocortex an...

MedKGent: a large language model agent framework for constructing temporally evolving medical knowledge graph

The rapid expansion of medical literature challenges the scalable structuring of domain knowledge. Knowledge Graphs (KGs) offer a solution, yet current construction methods lack generalizability and ignore the temporal dynamics of evolving knowledge. To address this, we introduce...

Single-cell atlas of reproductive endocrine organs reveals transcriptomic responses to type 1 diabetes mellitus in nonhuman primates

Abstract Type 1 diabetes mellitus characterized by insulin deficiency and hyperglycemia is associated with female subfertility. However, how hyperglycemia affects the hypothalamic-pituitary-ovarian-uterine axis remains poorly understood. In this study, we performed single-cell tr...

All-Optically Controlled Memristive Reservoir Computing Capable of Bipolar and Parallel Coding

Physical reservoir computing (RC) utilizes intrinsic dynamics of physical systems for efficient data processing. Emerging optoelectronic RC platforms merge the benefits of electronic and photonic computation. However, conventional designs are constrained by the unipolar photoresp...