Catholic University of Korea

Hyperacute Cytokine Kinetics and Early Interleukin-10 Elevation as Predictors of Neurological Outcome in Post-Cardiac Arrest Syndrome

Background: Post-cardiac arrest syndrome (PCAS) involves a complex interplay between systemic inflammatory and compensatory anti-inflammatory responses. The hyperacute kinetics of these cytokines and their incremental prognostic value beyond established brain injury biomarkers re...

Identification of a Pathogenic RECQL4 1.6-kb Deletion–Insertion in a Neonate with Atypical Skeletal Phenotype of Baller–Gerold Syndrome Using Rapid Whole-Genome Sequencing

Mi-Ae Jang, M.D., Ph.D., Ja-Hyun Jang, M.D., Ph.D., Jin Kyu Kim, M.D., Ph.D., Joonhong Park, M.D., Ph.D., Go Hun Seo, M.D., Ph.D., Misun Yang, M.D., Ph.D., Yun Sil Chang, M.D., Ph.D., and Hyun Ho Kim, M.D., Ph.D.. Ann Lab Med -0001;0:. https://doi.org/10.3343/alm.2026.0102

Original and Modified Sauvé–Kapandji Procedures: A Two-Axis Framework for Surgical Decision-Making—A Narrative Review

The Sauvé–Kapandji (SK) procedure is a salvage operation that fuses the distal radioulnar joint (DRUJ) and creates an intentional pseudarthrosis in the proximal ulna, thereby relieving pain while preserving forearm rotation and ulnar-sided bony support. This narrative review (1)...

Pulsed Field Versus Cryoballoon Ablation for Atrial Fibrillation: Procedural Outcomes and Hemolysis-Related Laboratory Changes in a Single-Center Pilot Study

Background and Objectives: Pulsed field ablation (PFA) and cryoballoon ablation (CRYO) are established approaches for pulmonary vein isolation in atrial fibrillation (AF). Given emerging concerns regarding hemolysis following PFA, this pilot study aims to directly compare outcome...

Multisensory Biophilic Experience in Virtual Retail Interiors: Effects of Visual and Auditory Stimuli on Visual Attention and Emotion

Advances in digital technology have facilitated the integration of biophilic design principles into retail interiors, presenting new opportunities to enhance consumer experiences. This study examines the impact of multisensory biophilic stimuli, specifically visual and auditory e...

Class- and dose-dependent heterogeneity in the risk of medication-related osteonecrosis of the jaw among antiresorptive agents: a nationwide new-user cohort study using Korean National Health Insurance claims data

Antiresorptive agents are widely used to treat osteoporosis and skeletal complications of malignancy, but long-term use can lead to medication-related osteonecrosis of the jaw (MRONJ). No nationwide Korean study has directly compared oral and intravenous bisphosphonates with low-...

Placental Growth Factor in Diabetic Retinopathy: Disease-Selective Signaling and Mechanistic Rationale for Targeted Therapy

Chronic hyperglycemia disrupts the retinal neurovascular unit, making diabetic retinopathy (DR) the leading cause of adult vision loss. The hallmarks of DR include pathological angiogenesis, vascular leakage, and neurodegeneration. Although vascular endothelial growth factor A (V...

Comparison of autologous platelet-rich plasma injection with air tamponade versus C3F8 tamponade in idiopathic full-thickness macular hole surgery

Vitrectomy, combined with internal limiting membrane peeling and gas tamponade, is the gold standard for treating full-thickness macular holes (FTMH). However, prolonged intraocular tamponade duration often causes patient discomfort and delays visual recovery, necessitating the n...

Optimal surgical margin and the efficacy of adjuvant radiotherapy in borderline and malignant phyllodes tumors: a multicenter retrospective study

Purpose: Optimal management of borderline and malignant phyllodes tumors (PT) is not well established, especially regarding margin width and the use of adjuvant radiotherapy (RT).This multicenter study aimed to identify prognostic factors and to assess the effectiveness of adjuva...

Cancer nanovaccine plus doxorubicin and immune checkpoint blockade overcomes chemoresistance and delays postsurgical recurrence

Chemotherapy for solid tumors has serious limitations due to acquired chemoresistance and frequent postsurgical recurrence. In this study, we developed a chemo-immunotherapy regimen combining a chemotherapeutic agent, a dendritic cell (DC)-activating cancer nanovaccine, and immun...

Calr-mediated calcium buffering: a molecular barrier to in vivo cardiac reprogramming

In a recent publication in Cell Stem Cell , Cai et al. 1 employed an in vivo Perturb-seq strategy to systematically identify molecular barriers that limit direct cardiac reprogramming following myocardial infarction (MI). This study provides a conceptual and technological framewo...

Early clinical outcomes of the trans-ocular threading technique for four-point flanged scleral fixation of intraocular lenses: a case series

Abstract Purpose To evaluate the early clinical outcomes and surgical feasibility of a trans-ocular threading technique for four-point flanged scleral fixation of intraocular lenses (IOLs). Methods This retrospective case series included 12 eyes of 12 patients who underwent four-...

Quantitative Evaluation of Geographic Atrophy Progression Using Geographic Atrophy Lesion Front Displacement

Purpose: To evaluate the temporal behavior and relative variability of a margin-based metric, lesion front displacement, for quantifying geographic atrophy (GA) progression secondary to age-related macular degeneration and to compare its performance with conventional metrics. Met...