Carl Zeiss (Germany)

Intrinsic OPTIR imaging and spectroscopy enable label-free monitoring of viral infection in living cells

Abstract Resolving biochemical signatures associated with viral infection progression within individual living cells, without introducing fluorescent labels that demand genetic accessibility and may perturb the process under study, remains a challenge for conventional optical app...

Sex-specific control of locomotor behavior by neuronal Arhgef10 in aged Drosophila

Mutations and polymorphisms in the Rho guanine nucleotide exchange factor 10 (ARHGEF10) locus are associated with behavioral and locomotor dysfunctions in humans, including psychiatric disorders and polyneuropathies that show age- and sex-specific prevalence. ARHGEF10 encodes a c...