Carl von Ossietzky Universität Oldenburg

Buoyancy and polarity driven accumulation of dissolved organic matter in the sea surface microlayer during a phytoplankton bloom

Abstract. The sea surface microlayer (SML) is only 1–1000 µm thick but resembles a biologically and geochemically very active boundary that modulates the exchange of energy and matter between the ocean and atmosphere. Globally, the SML accumulates up to 200 Tg C yr−1 of organic m...

Pediatric intensive care follow-up in Germany is rarely established and highly heterogeneous: a nationwide survey of 20 PICUs

BACKGROUND: Survival after pediatric critical illness has improved substantially, but many survivors and their families experience long-term physical, neurocognitive, psychological and social sequelae, summarized as post-intensive care syndrome in pediatrics and in families. Stru...

The Costs of Parkinson's Disease in Europe: Results of the Costs of Illness in Neurology Initiative

Abstract Background Parkinson's disease (PD) is the second most common neurodegenerative disease. It imposes substantial and growing burden on patients, families, and caregivers and reduces quality of life. The disability and care needs associated with PD carry economic ramificat...

Airborne measurements for investigating offshore wind farm wakes and modifications of sea state – benefits and limitations

Abstract. In the framework of the two large wind energy research projects WIPAFF and X-Wakes, crewed airborne measurements have been performed in and around wind farm clusters of the German Bight to investigate offshore wind farm wakes and associated sea-state modifications. Thes...

Accelerated long-term forgetting as an objective marker of subjective memory impairment in multiple sclerosis

Abstract Background Accelerated long-term forgetting (ALF), defined as an increased rate of memory loss over extended intervals, has so far been detected in a pilot study of patients with mild multiple sclerosis (MS). This study aimed to (I) confirm the presence of ALF in a large...

Gastropexy-Assisted vs. Gastropexy-Free Introducer Percutaneous Endoscopic Gastrostomy: A Prospective Randomized Trial

Introduction: Percutaneous endoscopic gastrostomy (PEG) is a well-established procedure for providing long-term enteral nutrition. Until recently, the only established introducer PEG involved the use of gastropexy sutures. In June 2021, an introducer PEG without gastropexy receiv...

A cardiovascular-motor axis framework for perfusion-mediated motor impairment

Cardiovascular disease is the leading cause of death worldwide, and among survivors of heart failure, peripheral arterial disease, valvular disease, and atrial fibrillation many develop motor impairment: weakness, slow gait, sarcopenia, frailty. These deficits are usually attribu...

A new species of Squamulea (Teloschistaceae) from the Himalayan Region

Squamulea pakistanica sp. nov. is a newly discovered lichen species from the Himalayan moist temperate forests of Pakistan. The genus Squamulea (Teloschistaceae) includes squamulose or subfoliose taxa, many of which are understudied in South Asia. This study aims to characterize...

Agranulocytosis associated with metamizole among EudraVigilance reports involving methotrexate for rheumatoid arthritis

Methotrexate (MTX) can induce adverse drug reactions (ADRs) including severe haematotoxic events. This study analyses whether agranulocytosis is disproportionately reported in spontaneous reports involving MTX for rheumatoid arthritis (RA) when use of metamizole, a non-opioid ana...

Delirium superimposed on dementia in nursing homes: prevalence, incidence, and prognosis – protocol of a prospective multicenter cohort study

Abstract Background Delirium is a frequent and serious neuropsychiatric syndrome in older adults. People living with dementia are at particularly high risk of developing delirium. In nursing homes, where dementia prevalence is high, delirium superimposed on dementia (DSD) represe...

Homicide at home: setting the agenda for an international collaboration to improve support for children bereaved due to family violence

Background: Bereavement due to fatal family violence (e.g. intimate partner homicide, filicide, parricide, siblicide) is a profoundly disruptive experience for children, with lifelong psychosocial consequences. Although the need for fatal family violence prevention is increasingl...

DECIDER-2: Prospective randomized multicenter phase III trial of decitabine and venetoclax administered in combination with all-trans retinoic acid or placebo in patients with acute myeloid leukemia who are ineligible for induction chemotherapy

Abstract Background Acute myeloid leukemia (AML) is predominantly a disease of older patients with a poor long-term survival. Approval of the combination of venetoclax (VEN) with azacitidine (AZA) or decitabine (DAC) in the European Union in 2021 for the treatment of patients wit...

Multiscale carrier-envelope phase characterization of 2-µm pulses delivered by a 200-kHz optical parametric amplifier

Abstract Light fields with a central wavelength of 2 µm are very well suited for strong-field-driven charge carrier control: Their photon energy lies far below the band gap of many materials, while their oscillation period remains significantly shorter than the coherence time of...

Back to the Future of qEEG: Lifespan Normative Modeling of Spectral Ratios and Functional Indices with Potential Applications to Therapeutic Monitoring

Quantitative EEG (qEEG) provides objective, millisecond-resolution measures of brain dynamics. Despite decades of methodological advances, clinically relevant derived indices-spectral power ratios, cognitive-emotional state markers, and physiological parameters-are typically repo...

Novel class identification: A human‐in‐the‐loop approach for efficient species recognition in bioacoustic data

Abstract Passive acoustic monitoring (PAM) is widely used to collect large‐scale wildlife data encompassing many species, but efficiently identifying all species—particularly rare and potentially endangered ones—without exhaustive manual examination of the entire dataset remains...