Bukhara State Medical Institute named after Abu Ali ibn Sino

Plant Disease and Phytopathogen Research in Central Asia: A Bibliometric Mapping of Research Trends, Collaboration, and Emerging Directions

Plant diseases and phytopathogenic threats pose significant challenges to agricultural productivity and food security in Kazakhstan, Kyrgyzstan, Tajikistan, Turkmenistan, and Uzbekistan. This study aimed to characterize research development, scientific productivity, collaboration...

A Prospective Clinical and Field Study Evaluating the Role of Salt Sensitivity Phenotyping in Guiding Antihypertensive Drug Selection and Reducing the Psychological Burden of Trial-And-Error Therapy

The objective of the prospective study was to investigate the significance of phenotypic characterization of salt sensitivity in the selection of initial antihypertensive therapy and its effect on blood pressure control among patients with stage 1 hypertension. Another aim was to...

Synergistic Effects of Culturally Adapted Mindful Movement on Pain Catastrophizing and Physical Function in Chronic Low Back Pain: A Randomized Controlled Trial

The current research was done with the aim to identify the joint effect of mindful movement program adapted to culture and translated into Uzbek on pain catastrophization and physical function in patients with chronic non-specific LBP. The design of this study was randomized cont...

Understanding the Psychosocial Factors Affecting Hypertension Management in Vulnerable Populations

This study conducted, was cross-sectional and carried out using a mixed approach to explore psychosocial determinants associated with the treatment of hypertension among vulnerable individuals in Uzbekistan. From March to August 2025, 320 patients suffering from hypertension with...

Quasi-3D Numerical Modeling of Groundwater Flow, Particle Transport, and Clogging-Induced Interlayer Leakage in Heterogeneous Multilayer Aquifers

Physical clogging during managed aquifer recharge can reduce aquifer conductivity and alter leakage across intervening aquitards. This study presents a quasi-three-dimensional model coupling horizontal groundwater flow, suspended-particle transport, retention, porosity and conduc...

Microbes in the dust: The ecology of arid soil microbiomes

Drylands now cover approximately 45% of Earth's terrestrial surface and are expanding under climate change, yet the microbial communities inhabiting these vast regions remain poorly integrated into ecosystem models. This review synthesizes current knowledge on arid soil microbiom...

Clinical-immunological phenotyping and score-based automated diagnostic support for chronic nonspecific upper urinary tract infections: a combined prospective-retrospective diagnostic study

Abstract Background Chronic nonspecific upper urinary tract infections (CNUTIs), including chronic pyelonephritis, are characterized by recurrent inflammation, persistent urinary abnormalities, and variable responses to conventional diagnostic and therapeutic approaches. Standard...

Diminished Ovarian Reserve in Advanced Endometriosis: Prevalence, Clinical Predictors, and Patient Awareness of Fertility Preservation

Background & Objective: Advanced endometriosis is recognized as a potential cause of Diminished Ovarian Reserve (DOR), yet data on its prevalence, predictors, and patient awareness in Central Asia are scarce. The present study was conducted with aim to determine the prevalence of...

Negative Results in Narcissism Interventions: A Meta-Analytic Review of Replication Failures in Social Media De-Addiction Programs

This study aim to assess the true effect size of digital addiction cessation intervention in reducing narcissism as well as sources of heterogeneity and publication bias in this field. Meta-analysis of all relevant research that followed the PRISMA 2020 guideline was performed on...

A Psychosocial Perspective on Sedentary Behavior and Workplace Health: The Role of Physical Activity in Reducing Hypertension Risk Among Office Workers

The purpose of this study which has been done through a cross-sectional-analytic, was to examine the correlation between physical activity and the occurrence of hypertension among Jordanian office workers. Another objective of the research was to investigate the psychological and...

CLINICAL AND EPIDEMIOLOGICAL CHARACTERISTICS OF PARASITIC DISEASES IN ADULTS: DIAGNOSTIC PATTERNS AND STATISTICAL ANALYSIS

Parasitic infections remain a significant public health issue among adults, often presenting with vague or chronic clinical manifestations. This study evaluated the clinical and epidemiological features of parasitic diseases in 250 patients aged 18–60 years. Comprehensive laborat...

Time to pacemaker insertion in older adults: A perspective on mortality and functional outcomes

Pacemaker insertion is common in older adults, yet the implications of procedural delays remain unclear. Nguyen and colleagues reported that longer time to implantation was associated with increased mortality over nearly five years. While this contribution is valuable, several me...

Status and ontogenetic structure of Codonopsis bactriana (Campanulaceae) in southwestern Uzbekistan

Codonopsis bactriana F.O. Khass., U. Kodyrov & A. Myrz. is a rare endemic medicinal species distributed in the mountainous regions of southwestern Uzbekistan. The present study aimed to assess the current status and ontogenetic structure of natural populations of C. bactriana und...

Status and ontogenetic structure of Codonopsis bactriana (Campanulaceae) in southwestern Uzbekistan

Codonopsis bactriana F.O. Khass., U. Kodyrov & A. Myrz. is a rare endemic medicinal species distributed in the mountainous regions of southwestern Uzbekistan. The present study aimed to assess the current status and ontogenetic structure of natural populations of C. bactriana und...

Altitudinal patterns of soil nematode community diversity and functional structure in the Boysun Mountains, Uzbekistan

Mountain ecosystems provide natural gradients for investigating biodiversity responses to environmental variation. This study examined the effects of altitude on the taxonomic diversity, trophic structure, and functional composition of soil nematode communities in the Boysun Moun...

Altitudinal patterns of soil nematode community diversity and functional structure in the Boysun Mountains, Uzbekistan

Mountain ecosystems provide natural gradients for investigating biodiversity responses to environmental variation. This study examined the effects of altitude on the taxonomic diversity, trophic structure, and functional composition of soil nematode communities in the Boysun Moun...

Independent Engineering Transfer After Traceable Generative-AI-Assisted Learning: A Six-University Controlled Trial with Deterministic Cluster Allocation in Agricultural Engineering Education

Generative artificial intelligence (GenAI) can support engineering problem solving, but whether AI-assisted practice transfers to independent performance after the tool is removed remains unclear. This multicentre controlled trial evaluated a traceable five-stage GenAI-assisted l...

IMMUNOHISTOCHEMICAL EXAMINATION OF GASTRIC TISSUE IN LIVER INJURY UNDER EXPERIMENTAL CONDITIONS

The expression of the Ki-67 proliferation marker is an important criterion for assessing the proliferative activity of gastric mucosa cells. During the study, the level of immunohistochemical expression of the Ki-67 marker in the gastric tissues of 3 and 6-month-old white crossbr...

Assessment of the Dissipative Properties of Viscoelastic Hollow Cylindrical Bodies with Filler During the Propagation of Natural Waves

Searching by numerical simulation for structures with optimal damping properties among viscoelastic hollow cylindrical bodies with a filler is usually associated with a large amount of computation. Formulating the mechanical problem as one of natural vibrations and natural wave p...

A tumor microenvironment acid-responsive therapy combining fenton chemistry and chemotherapy via TNF pathway for synergistic and safe lung cancer treatment

Lung cancer is one of the most common malignant tumors, but traditional treatments, particularly chemotherapy, often face significant challenges, including drug resistance and high systemic toxicity. In this study, we developed a novel acid responsive nanoparticle, La₂O₃@PDA/PTX,...