B.S. Abdur Rahman Crescent Institute of Science & Technology

Taurine is a functional regulator of transthyretin; implication in transthyretin-induced hypothyroidism and amyloidosis

Transthyretin (TTR) is a homo-tetrameric, 55 kDa, transport protein synthesized mainly in the liver, retinal epithelium, choroid plexus, placental villi and uterus. The main function of TTR is transport of thyroxine (T 4 ) and retinol-binding protein, while it also plays a crucia...

Evaluating the Impact of AI-Enabled Appraisal Practices on Millennial Career Advancement: A Gender Equality Perspective in Mumbai Workplaces

Abstract The increasing integration of Artificial Intelligence (AI) into human resource management has transformed traditional performance appraisal through data-driven evaluation, continuous feedback, predictive analytics, and automated decision-making. This study evaluates the...

Performance assessment and parametric analysis of CFST columns with various concrete infills

This study investigated the structural behaviour of Concrete Filled Steel Tubular (CFST) columns under axial compression using two infill materials: Lightweight Concrete (LWC) and Hybrid Fibre-Reinforced Concrete (HFRC). In Phase I, the LWC mix was developed by partially replacin...

Hydrogel‐Based Mechano‐Immunomodulation in Bone Fracture Healing: Mechanical Regulation of Macrophage Phenotypes, Osteoimmune Interactions, and Regeneration

Bone fracture healing is a meticulously regulated process encompassing the inflammatory, reparative, and remodelling phases. Macrophages serve as pivotal coordinators within this cascade, with their polarisation from pro-inflammatory M1 to proregenerative M2 phenotypes, which pla...

Clove oil nanoemulsion as a delivery system for Acmella oleracea mediated silver nanoparticles to curtail growth and biofilm in bacterial pathogens causing dental caries

Abstract Dental issues are a global concern affecting individuals of all ages. Oral microorganisms, including Streptococcus mutans and Enterococcus faecalis , contribute to gum inflammation and tooth detachment by forming biofilms that demineralize enamel and promote denture biof...

Plant-mediated fabrication of Ag/TiO₂ bimetallic nanoparticles with anti-diabetic and anti-Inflammatory activities: Computational and experimental investigation

Globally, diabetes affects 589 million people and is a severe health epidemic, especially in regions where its incidence remains rising. The main challenge is the increase in diabetic complications and antibiotic resistance linked to conventional treatments. Bi-metallic nanoparti...