Bezmiâlem Vakıf Üniversitesi

Bleeding Control in Zygomatic Aneurysmal Bone Cysts: Intraoperative Ligation as an Alternative to Preoperative Embolization

OBJECTIVES: Zygomatic aneurysmal bone cysts (ABCs) are rare lesions that may lead to significant intraoperative bleeding. Although preoperative selective arterial embolization (SAE) is often recommended for hemorrhage control, it may not always be feasible. This report explores i...

Comparison of Methylprednisolone and Dexamethasone in Their Interaction With Sugammadex in Pediatric Patients: A Randomized Controlled Trial

ABSTRACT Background Sugammadex may interact with steroidal compounds; however, comparative clinical data on different peri‐operative corticosteroids in children are limited. This randomized controlled trial primarily aimed to compare the effect of methylprednisolone and dexametha...

Integrated genome-wide DNA methylation and transcriptomic analysis prioritizes EPHA5 as a candidate non-invasive epigenetic biomarker for oral squamous cell carcinoma

Purpose Oral squamous cell carcinoma (OSCC) remains a major clinical challenge because of delayed diagnosis and the lack of validated non-invasive biomarkers for OSCC detection. Epigenetic alterations during oral carcinogenesis represent promising biomarker candidates. This study...

Effects of virtual reality-based aerobic exercise versus traditional aerobic exercise training on physical fitness, functional capacity, and quality of life in individuals with Down syndrome: DOWNFIT (Down Syndrome Fitness Intervention Trial) randomized controlled trial

Purpose To compare the effects of virtual reality-based aerobic exercise (VR-AE) and traditional aerobic exercise (TAE) on on physical fitness, functional capacity, and quality of life (QoL) in adolescents with Down syndrome (DS).Methods Forty adolescents with DS (mean age 14.45...

Follicular-Fluid Organic Acid Profiling in Polyendocrine Metabolic Ovarian Syndrome, Poor Responders, and Controls

Follicular-fluid (FF) organic acid concentrations may differ among women with normal ovarian reserve (NOR), polyendocrine metabolic ovarian syndrome (PMOS), and poor ovarian response (POR), reflecting alterations in central carbon and amino-acid-related metabolic pathways. PMOS a...

Coronary Artery Perforation During Percutaneous Coronary Intervention: A Two-Center Real-World Case Series and Review of Management Strategies

BACKGROUND: Coronary artery perforation (CAP) is a rare life-threatening complication of percutaneous coronary intervention (PCI). Although several risk factors for CAP have been described, real-world multicenter studies analyzing the clinical outcomes remain limited. This study...

Evaluation of the pSOFA Score in a Pediatric Intensive Care Unit and Its Discriminative Performance Compared with PRISM 4 and PIM 3

Objectives: We aimed to evaluate the performance of the age-adapted Pediatric Sequential Organ Failure Assessment (pSOFA) score, as a predictor of mortality in patients admitted to pediatric intensive care units (PICUs), and to compare it with the Pediatric Risk of Mortality 4 (P...

Fenugreek ( Trigonella foenum‐graecum L.) as a functional food associated with improved heat‐stress survival in Caenorhabditis elegans

Abstract BACKGROUND Fenugreek ( Trigonella foenum‐graecum L.) is widely consumed as a functional food across Mediterranean, Middle Eastern, and South Asian cultures and has long been valued in traditional diets for its health‐promoting properties. Although fenugreek contains dive...

Predictive value of metabolic and tumor dissemination parameters in diffuse large B-cell lymphoma: can relapse be predicted despite adequate interim PET response?

OBJECTIVE: To evaluate associations of baseline and interim fluorine-18 fluorodeoxyglucose PET/computed tomography parameters with early clinical outcomes in diffuse large B-cell lymphoma (DLBCL) and identify prognostic/predictive biomarkers, including predictors of discordance b...

Effect of aging on cavity adaptation of Class V cavities restored with bioactive restorative materials: a Micro-CT and SEM analysis

This in vitro study evaluated the effect of aging on cavity adaptation (marginal vs. interfacial) of Class V cavities restored with bioactive restorative materials using micro-computed tomography (micro-CT) and scanning electron microscopy (SEM). Thirty-six sound human molars rec...

Prognostic performance of the albumin–gluteus medius index for one-year mortality in geriatric hip fracture patients: a retrospective cohort study

Proximal femur fractures are associated with high mortality in older adults, and accurate prognostic assessment is clinically important. The Albumin–Gluteus Medius Index (AGMI) is a novel composite index integrating CT-derived muscle reserve with serum albumin, an inflammatory an...

Effect of Angulated Screw Channel (ASC) design on the fracture resistance of implant-supported monolithic zirconia and lithium disilicate crowns: an in vitro study

Ti-base abutments with angulated screw channel (ASC) designs have been developed to address the esthetic challenges associated with labial screw access in anterior implant-supported single crowns, as well as the ergonomic limitations caused by restricted mouth opening in posterio...

Efficacy of Beta-Aminopropionitrile, Contractubex®, Nigella sativa Oil, Aloe Vera Oil, and Soybean Oil in Preventing Postoperative Adhesions in an Experimental Thyroidectomy Model

<title>Abstract</title> Background/Aim: Adhesions in reoperative thyroid surgery lead to prolonged operation times and an increase in postoperative complications. The use of anti-adhesive agents during the initial surgery may reduce the incidence of recurrent laryngeal nerve inju...

Cone-Beam Computed Tomography-Based Anatomic Mapping of Maxillofacial Foramina: Development of a Novel Proportional Guide for Facial Aesthetic Procedures

OBJECTIVE: Anatomic safety and aesthetic harmony are of critical importance in facial aesthetics and surgical procedures. This study aims to evaluate whether the distance ratios among the supraorbital, infraorbital, and mental foramina conform to the golden ratio (φ=1.618). METHO...

Preoperative Naples Prognostic Score and outcomes after isolated coronary artery bypass grafting: a retrospective cohort study

Inflammatory and nutritional status may refine risk assessment before coronary artery bypass grafting (CABG). This study evaluated the association between preoperative Naples Prognostic Score (NPS) and early and follow-up outcomes after isolated CABG. This single-center retrospec...

Integrated Prognostic Stratification After Perioperative FLOT in Gastric and Gastroesophageal Junction Adenocarcinoma: A Multicenter Real-World Study

Background/Objectives: Outcomes after perioperative FLOT for gastric and gastroesophageal junction adenocarcinoma remain variable, even among patients treated with curative intent. Although postoperative pathological findings are central to risk assessment, they do not fully capt...

Age-related effects of comprehensive in-patient physiotherapy after lung cancer surgery across age groups: an ambispective observational cohort study in middle-aged and older patients

Abstract Background Postoperative recovery after lung cancer surgery may be influenced by age, comorbidity burden, and perioperative rehabilitation strategies. However, evidence regarding the age-related effects of structured early inpatient physiotherapy programs remains limited...

Exploring Immersive Virtual Reality as an Approach to Improve School Participation–Related Constructs in Children With ADHD

ABSTRACT Background School participation is frequency and involvement from person–environment transactions, not diagnosis, per the International Classification of Functioning, Disability and Health (ICF) and the family of participation‐related constructs (fPRC). In this framework...

Effectiveness of Movement Representation Techniques in Chronic Non-Specific Spinal Pain: A Systematic Review and Meta-Analysis

Background and Objectives: Movement representation techniques (MRTs), including motor imagery and mirror therapy, have been investigated in several chronic pain conditions; however, their effectiveness in chronic non-specific spinal pain (CNSP) has not been specifically synthesiz...

Evaluation of postoperative pain associated with different working length determination methods: a randomised clinical study

Abstract Background Postoperative pain is a common concern in endodontic treatment. In teeth with asymptomatic irreversible pulpitis, accurate working length determination is critical for effective root canal therapy and may influence postoperative discomfort. This study compared...