Beijing University of Chinese Medicine

Characterizing Shared Sensory Priorities and Age-Group Differences for Feng-Flavor Baijiu: A Consumer Survey Using Hierarchical Weighting and Interpretable Machine Learning

As Feng-flavor Baijiu increasingly shifts toward consumer-oriented product development, clarifying consumers’ shared sensory priorities and age-related differences is essential for aligning its traditional style with evolving market demands. This study collected 1523 questionnair...

Maxing Loushi Decoction alleviates COPD by targeting the PD-1/PD-L1 pathway: restoring Th17/Treg balance and inhibiting ferroptosis

Chronic obstructive pulmonary disease (COPD) is a progressive respiratory disorder driven by immune dysregulation and ferroptosis, with limited therapies addressing its underlying pathogenesis. Maxing Loushi Decoction (MXLS), a modified traditional Chinese medicine (TCM) formula,...

Risk factors and prevalence of incontinence-associated dermatitis in elderly patients: a meta-analysis and systematic review

This systematic review aimed to evaluate the prevalence and risk factors of Incontinence-Associated Dermatitis (IAD) in elderly patients. A systematic search was conducted across 10 databases, including PubMed, Embase, Web of Science, Cochrane Library, CINAHL, Ovid MEDLINE, Scopu...

Preclinical evidence of neuroprotective effects of endocannabinoids and related lipid molecules in ischemic stroke: a systematic review and meta-analysis of animal studies

Background Ischemic stroke is an acute cerebrovascular disorder caused by interruption of cerebral blood supply, frequently resulting in severe neurological deficits. However, effective therapeutic strategies remain limited. Recent studies have demonstrated that endocannabinoids...

Inadequate Reporting of Harms in RCTs of Chinese Herbal Medicine Formulas: A Systematic Survey of Leading Medical Journals

ABSTRACT Objective To evaluate harms reporting practices in placebo‐controlled randomized clinical trials (RCTs) of Chinese herbal medicine (CHM) formulas published in Quartile 1 (Q1) English‐language and Tier‐1 Chinese journals. Methods This systematic survey evaluated harms rep...

Metabolic-extracellular matrix crosstalk in hepatocellular carcinoma: mechanisms and targeted intervention

Bidirectional crosstalk between metabolic reprogramming and extracellular matrix (ECM) remodeling in hepatocellular carcinoma (HCC) constitutes an important metabolic–ECM regulatory network that contributes to HCC progression. Metabolic derangements disrupt ECM deposition, crossl...

Domino Effect in Epimer Self‐Assembly Induces Diverse Hydrogel Properties for Biomedical Applications

ABSTRACT Precise regulation of small‐molecule self‐assembly remains a formidable challenge, as subtle structural variations can trigger profound reprogramming of supramolecular architectures. Herein, we demonstrate that C18‐epimerization of glycyrrhizic acid (GA) acts as a molecu...

Mulberry Leaf Water Extract Ameliorates Impaired Glucose Tolerance via the Gut Microbiota/SCFAs/AMPKα1 Axis in Adipose Tissue

Background/Objectives: Impaired glucose tolerance (IGT) is a prediabetic condition affecting over 600 million adults worldwide. Mulberry leaf (Morus alba L.) has shown antidiabetic potential, but whether adipose AMPKα1 is required for its effects remains unclear. This study aimed...