Beijing Tongren Hospital

Uncertainty-inspired open-set model for identifying infantile fundus abnormalities

Accurate and safe identification of infantile fundus abnormalities is critical for large-scale screening, yet remains challenging because of heterogeneous disease presentations and overconfident predictions by conventional artificial intelligence (AI) models. In this study, we ai...

Aqueous Humor Proteomics Reveals the Molecular Basis for Differential Treatment Responses in nAMD and pmCNV

Purpose: Choroidal neovascularization (CNV) causes vision loss in neovascular age-related macular degeneration (nAMD) and pathologic myopia-related CNV (pmCNV). Despite shared clinical features, they respond differently to treatment. This study compared aqueous humor (AH) proteom...

Analysis of the application of computerized optokinetic nystagmus analyzer in vision examination

To investigate the practicability, accuracy, and consistency of the computerized optokinetic nystagmus (OKN) analyzer for visual acuity (VA) measurement. Cross-sectional consistency evaluation study. A total of 219 subjects (13.48 ± 12.89 years, 115 males, 104 females) underwent...

wbp-encoded LPS O-antigen architecture as a prognostic and therapeutic target in Pseudomonas aeruginosa keratitis

Background Pseudomonas aeruginosa ( P. aeruginosa ) keratitis can progress rapidly to vision-threatening disease, even with intensive therapy. Virulence-associated genes are key determinants of ocular-surface pathogenesis. We therefore sought to develop a composite wbp-exo genoty...

The association between the availability of health guidance and self-management activities among patients with type 2 diabetes: a generalized linear mixed model incorporating patient- and GP-level factors

The availability of health guidance (AHG) provided by general practitioners (GPs) may vary in complex primary care settings. This study aimed to assess the AHG for patients with type 2 diabetes mellitus (T2DM) in general practice setting and examine the association between AHG an...

Development of machine learning models for predicting delirium in elderly patients after thoracic surgeries

Postoperative delirium (POD) is a frequent neurological complication following anesthesia and surgery, which is associated with increased comorbidities and mortality. The current study developed and internally validated a machine learning model for predicting POD in elderly patie...

HE-referenced eosinophil assessment and cutoff estimation using Congo red and Chromotrope 2R staining in chronic rhinosinusitis with nasal polyps

Abstract This cross-sectional histopathological study aimed to compare eosinophil visualization and quantification using Congo red, Chromotrope 2R, and conventional hematoxylin–eosin (HE) staining in chronic rhinosinusitis with nasal polyps (CRSwNP), and to explore HE-referenced...

Articulating Hem-o-Lok–assisted single-position laparoscopic nephroureterectomy for UTUC: a feasibility study with preliminary oncological outcomes

Radical nephroureterectomy (RNU) with bladder cuff excision is the standard treatment for high-risk non-metastatic upper tract urothelial carcinoma (UTUC). This feasibility-oriented study aimed to describe articulating Hem-o-Lok–assisted single-position laparoscopic nephrouretere...

Contractile morning glory disc anomaly associated with total retinal detachment: a case report

Morning glory disc anomaly is a rare congenital optic nerve head malformation. The contractile variant, characterized by rhythmic pulsatile movement of the optic disc, is exceptionally uncommon, and detailed documentation of its dynamic features using multimodal imaging remains l...

Risk factors and predictors for botulinum toxin type A reinjection within six months in patients with acute acquired concomitant esotropia

BACKGROUND: To identify independent risk factors and predictors for botulinum toxin type A (BTA) reinjection within 6 months in acute acquired concomitant esotropia (AACE) patients, providing a scientific foundation for risk-stratified clinical management. METHODS: In this case-c...