Azienda Ospedale - Università Padova

Beyond intramuscular nerve blockade: a complementary perspective on the anatomic basis of the PENG block

We read with great interest the study by Gautier and colleagues, which used a multimodal approach combining gross dissection, cryo-cross-sectional analysis, and histology to characterize injectate distribution following the pericapsular nerve group (PENG) block.[1][1] The methodo...

Evaluating the Role of MC1R Variants in Cutaneous and Ocular Phenotypes: A Candidate TYR–MC1R Genetic Interaction in Oculocutaneous Disorders

Background: The melanocortin-1 receptor (MC1R) gene is a major determinant of skin and hair color. Although several MC1R variants increase the risk of skin tumors regardless of pigmentation, their role as genetic modifiers in ocular diseases remains poorly understood. Methods: He...

Navigating an Inevitable Transformation: A Reflection on Responsible Scientific Writing Large Language Models Integration and the RULE-AP Consensus

Large language models (LLMs) are reshaping scientific communication in Anesthesiology and Pain Medicine. The RULE-AP Delphi consensus – convening 53 editors-in-chief – proposes a regulatory framework that distinguishes legitimate assistance from intellectual abdication. We argue...

Dietary and Parenteral Nutritional Management of Short Bowel Syndrome with Intestinal Failure in Adults: A Narrative Review

Short bowel syndrome (SBS) is the leading cause of chronic intestinal failure in adults, arising when the residual small bowel can no longer absorb the macronutrients, water, and electrolytes needed to sustain health without intravenous supplementation. Its management is, at its...

A Review on Current Challenges and Knowledge Gaps in Artificial Stone Silicosis

BACKGROUND: The global emergence of artificial stone (AS) silicosis represents a critical occupational health challenge. The aim of this systematic review is to provide an overview of the clinical, functional, radiological, and occupational characteristics of patients affected by...

Frailty and longitudinal pulmonary function trajectories in lung transplant recipients

Abstract Background Frailty is increasingly recognized as a marker of biological vulnerability associated with adverse clinical outcomes. Lung transplant recipients may be particularly susceptible to frailty, yet its impact on longitudinal pulmonary function improvement after tra...

Pediatric Arboviral Infections in Europe: Epidemiology, Clinical Features, Diagnosis and Prevention

Arboviral infections, including West Nile virus (WNV), dengue virus (DENV), chikungunya virus (CHIKV), Zika virus (ZIKV), and, to a lesser extent, Oropouche virus (OROV), pose a heterogeneous and evolving challenge for pediatric health in Europe. The increasing presence of compet...

Estimating the Extent of Missed Opportunities for Osteoporosis Treatment Before Hip Fracture Occurrence

Abstract Hip fractures (HF) are among the most serious consequences of osteoporosis. Many individuals who subsequently sustain a HF may already fulfill recognized criteria for fracture risk assessment, bone mineral density (BMD) evaluation, or anti-osteoporosis treatment before t...

Healing Following Endoscopic Reconstruction of the Anterior Skull Base in Patients With Sinonasal Malignancies

ABSTRACT Background Healing dynamics after anterior skull base (ASB) reconstruction following transnasal endoscopic surgery (TES) for sinonasal malignancies remain poorly characterized. This study aimed to describe the postoperative healing process, quantify time to healing, iden...