Institution
Astana Medical University
Recent research
- Health & MedicineOpen access
Background To compare literature findings about functional, oncological and surgical outcomes of transoral robotic (TORS) versus transoral laser microsurgery (TOLM) for supraglottic cT1-T3 laryngeal cancers. Methods Three independent investigators conducted a PubMed, Scopus, and...
- Materials & EnergyOpen access
The contamination of water resources by heavy metals, radionuclides, and organic pollutants demands efficient materials for water treatment. Covalent organic frameworks (COFs) are promising candidates owing to their tunable porosity and functionalizable frameworks. This review ex...
- Engineering & TechnologyOpen access
Climate-neutrality planning requires modeling tools that connect long-term investment, multi-sector demand and emissions, power-system operation, and grid-security assessment. This structured review examines six widely used platforms such as PyPSA, Julia/JuMP, GAMS, TIMES, DIgSIL...
- Health & MedicineOpen access
Background: Tuberculosis (TB) mortality remains an important indicator of disease burden, health system performance, and progress toward global TB control targets. This study aimed to assess long-term trends in TB mortality in Kazakhstan from 1998 to 2024 and to examine regional...
- Climate & EnvironmentOpen access
Waste-derived natural polymers offer a route to low-cost sorbents for toxic metal ions, but reported performance is difficult to compare because precursor composition, polymer processing, modification, and experimental conditions vary widely. This critical review examines silk fi...
- Climate & EnvironmentOpen access
The Kalba Ridge in eastern Kazakhstan is a transitional forest-steppe system in which woody vegetation forms a mosaic of forest, shrub, meadow, steppe, and riparian habitats. We analysed a presence/absence matrix of 76 woody taxa across 11 plant complexes grouped into eastern, ce...
- Health & MedicineOpen access
Background/Objectives: Long-run facility-level perinatal data from Central Asia are scarce. We described eleven years of stillbirth, neonatal, infant and perinatal mortality at one tertiary maternity center in Kazakhstan, and used the Birthweight and Age-at-death Boxes for Interv...
- BiologyOpen access
Esophageal cancer represent a major global health concern. Esophageal squamous cell carcinoma (ESCC) is the most prevalent histological subtype and exhibits pronounced population-specific variation in incidence. Unfortunately, the main cause of this geographical difference in dis...
- Materials & EnergyOpen access
The petroliferous Aryskum Depression, located within the South Torgai Basin, Kazakhstan, comprises several grabens up to 6 km deep, separated by horsts with more than 4 km of structural relief. Spatial analysis of reported reservoir and measured bottomhole temperatures from oil a...
- Health & MedicineOpen access
Cardiovascular diseases (CVDs) are the leading cause of death worldwide. While the impact of COVID-19 on trends is recognized, it is uncertain whether these patterns continued into the third pandemic year. This study sought to investigate the mortality patterns of CVDs during 201...
- Health & MedicineOpen access
Current Advances in Liver-Targeted Drug Delivery: Synthetic, Biological, and Biomimetic Platforms
Liver-targeted drug delivery offers opportunities to increase therapeutic exposure at sites of hepatic disease while limiting systemic toxicity; however, successful targeting requires more than preferential accumulation of a carrier within the liver. This narrative review critica...
- Society & EconomicsOpen access
Oil-exporting economies are notoriously sensitive to external shocks, but the importance of current oil revenue absorption for macroeconomic shock transmission has not been explored thoroughly. This paper constructs a stylized DSGE model to analyze how macroeconomic shock propaga...
- Society & EconomicsOpen access
Cyberbullying that escalates into a victim's suicide poses significant challenges at the intersection of criminal law, causation analysis, and digital forensics. This article aims to examine how four jurisdictions - Kazakhstan, the United States, Germany, and India - conceptualis...
- BiologyOpen access
The growing volume of unstructured clinical and genetic text calls for automated processing methods that can meaningfully support clinical decision-making. Most existing work, however, treats the analysis of patient clinical descriptions and the interpretation of genetic reports...
- Materials & EnergyOpen access
Unsaturated polyester resins (UPRs) represent challenging systems for reversible-deactivation radical polymerization (RDRP) because chain propagation, branching, and localized gelation may occur concurrently. This study systematically investigates the influence of the concentrati...
- Climate & EnvironmentOpen access
Abstract In March 2024, the Republic of Kazakhstan unified its administrative time to UTC + 5, creating a nationwide natural experiment across a 30-degree longitudinal gradient. This structural shift offered a rare opportunity to evaluate how abrupt temporal restructuring correla...
- Health & MedicineOpen access
Background/Objectives: GWASs have identified more than 250 prostate cancer (PCa) predisposition loci, predominantly in European and partly Asian cohorts. The Kazakh population is markedly under-represented in international genetic studies, limiting existing risk models. This stud...
- Health & MedicineOpen access
MSC–Hydrogel Composite Systems for Knee Cartilage Repair and Osteoarthritis: A Systematic Review
Background: MSC–hydrogel composite systems were developed to overcome the poor cell retention and limited durability of conventional marrow stimulation and suspension-based MSC delivery. A rigorous synthesis of the clinical evidence is lacking. Objectives: To evaluate the safety...
- BiologyOpen access
Dactylorhiza fuchsii (Druce) Soó is an ecologically sensitive terrestrial orchid and an important indicator of habitat condition, yet its population structure and morphological variability remain poorly studied in the Central Kazakh Uplands. This study evaluated the population si...
- BiologyOpen access
Acinetobacter baumannii is a critical WHO priority pathogen due to its multidrug resistance and high mortality in carbapenem-resistant infections. Resistance is predominantly mediated by class D carbapenemase genes blaOXA-23 and blaOXA-40, which spread rapidly via horizontal gene...