Assiut University

Knowledge, attitudes, and practices (KAP) toward stroke prevention among hypertensive patients in Egypt: a multicenter cross-sectional study

Abstract Stroke is the second most common cause of death worldwide and represents a major health concern in Egypt. Hypertension is the most important modifiable risk factor for stroke; we aim to assess knowledge, attitudes, and practices (KAP) toward stroke prevention among hyper...

Phytochemical-capped silver nanoparticles as functional antiviral nanomaterials: Computational and experimental analysis of nano–bio interactions with SARS-CoV-2 targets

The emergence of SARS-CoV-2 variants highlights the need for antiviral strategies integrating molecular inhibitors and nanostructured materials. This study employed a computational and network pharmacology approach to investigate clinically approved SARS-CoV-2 protease inhibitors...

Retinal optical coherence tomography angiography findings in the new- onset migraine patients: a prospective case-control study

the purpose of this study is to evaluate both macular thickness and vascular density in patients with new- onset migraine using optical coherence tomography angiography (OCTA). This prospective case-control study included 109 participants divided into two groups: Group (A), which...

Evaluation of the new Egyptian undergraduate medical program from students’ perspectives: a nationwide cross-sectional study

Abstract Background The global emphasis on medical education reform highlights the need for essential competencies to meet evolving healthcare demands. In Egypt, significant reforms in 2018 introduced a competency-based, integrated undergraduate medical curriculum—a five-year pro...

Comprehensive Physicochemical Characterization and Pyrolysis Kinetics of Halfa Grass ( Desmostachya bipinnata ) for Sustainable Bioenergy Applications

ABSTRACT Halfa grass ( Desmostachya bipinnata ) is an abundant lignocellulosic biomass with potential for thermochemical conversion and biochar production. This study investigated its physicochemical characteristics, pyrolysis kinetics, reaction mechanism, and thermodynamic behav...

Dexmedetomidine versus No-sedation for Agitation Control in COPD Patients receiving Noninvasive Ventilation: a Randomized Trial

Abstract Background Agitation occurs in 20–50% of ICU patients and can lead to failure of noninvasive ventilation (NIV). The use of benzodiazepines poses a risk of respiratory depression, which makes dexmedetomidine use in COPD patients a suitable alternative despite its haemodyn...

Talaromyces marinus (Eurotiales, Trichocomaceae): a new marine fungus from the Red Sea, Egypt, with distinguished enzymatic capabilities

Abstract Background Talaromyces is a large and taxonomically important genus within Ascomycota, established to accommodate the teleomorphs of certain Penicillium species and now recognized as a monophyletic lineage distinct from Penicillium . Multigene analyses demonstrated that...

Extensively drug-resistant ESBL-producing enterobacterales and coexisting antimicrobial resistance genes are associated with mortality in critically ill patients with cancer

Abstract ESBL-producing bacteria are a problem in patients with cancer. The emergence of XDR phenotypes with ESBLs increases mortality. We aimed to evaluate ESBL-producing bacteria, the prevalence of MDR and XDR phenotypes, ESBL genes, and mortality predictors in patients with ca...

Clinical integration of trabecular bone score in precision osteoporosis care: a position statement by the Egyptian academy of bone and muscle health

Abstract Background Dual-energy X-ray absorptiometry (DXA)-derived bone mineral density (BMD) has long been the gold standard for osteoporosis diagnosis, yet its inability to account for bone quality leads to a significant “sensitivity gap” in fracture risk prediction. This posit...

Secure UPnP Resource Discovery Using a PUF-Assisted Hardware Accelerator for IoT

Universal Plug and Play (UPnP) is widely used for resource discovery in internet of things and smart-edge environments because of its lightweight and decentralized operation. However, conventional UPnP and Simple Service Discovery Protocol (SSDP) mechanisms expose static identifi...

A Surgical Algorithm for Upper Cervical Trauma Based on the AO Spine Upper Cervical Injury Classification System

Study Design. Global cross-sectional survey Objective. To establish a surgical algorithm for upper cervical spine injuries using the AO Spine Upper Cervical Injury Classification (UCIC) system, defining operative thresholds using a novel proposed Upper Cervical AO-Spine Injury Sc...

Decoding the causes of ischemic stroke despite ongoing oral anticoagulation and their clinical impact: the ASPERA-R study

BACKGROUND: Oral anticoagulants (OACs), including vitamin K antagonists and direct OACs, reduce stroke risk in atrial fibrillation (AF), yet breakthrough ischemic stroke still occurs in 1-2% of patients annually despite adequate therapy. The mechanisms underlying these events rem...

Angiographic and early in-hospital profile of primary percutaneous coronary intervention in patients with substance use disorder presenting with ST-segment elevation myocardial infarction

Abstract Acute myocardial infarction is increasingly recognized in younger adults, but the angiographic and early clinical profile of ST-segment elevation myocardial infarction among patients with substance use disorder remains incompletely defined. This single-center prospective...

Sustainable Leadership, Workplace Integration, and Resilience Among Staff Nurses: A Cross-Sectional Correlational Study

Background: Sustainable leadership has emerged as a critical approach for promoting long-term organizational effectiveness and workforce well-being in healthcare settings. However, empirical evidence linking sustainable leadership to workplace integration and resilience among nur...

Evaluation of the new Egyptian undergraduate medical program from the perspectives of faculty and institutional leadership: a nationwide, mixed-method study

Abstract Background In response to global calls for medical education reform, Egypt restructured its national undergraduate medical education program from a 6 + 1 model to a competency-based “5 + 2” model. This reformed program emphasizes early clinical exposure, integration of b...

Validation of the AO Spine Osteoporotic Fracture Classification—effect of geographical region on reliability and reproducibility

Regional differences affect the reliability of the AO Spine-DGOU Osteoporotic Fracture Classification. European participants showed the highest agreement. This study underscores the need for addressing regional factors to improve the system’s global clinical utility. To evaluate...

Efficacy and Safety of Baxdrostat for Patients With Uncontrolled or Resistant Hypertension: A Systematic Review and Meta-Analysis

We evaluated the efficacy and safety of baxdrostat in adults with uncontrolled or resistant hypertension. We searched PubMed, Scopus, Web of Science, and Cochrane CENTRAL from inception to January 2026. We included randomized controlled trials that involved hypertension patients...

Laparoscopic Burch Colposuspension Versus Transobturator Tape for the Treatment of Stress Urinary Incontinence in Egyptian Women: A 12‐Month Randomized Controlled Trial

AIMS: This study aimed to compare the efficacy, safety, and patient-reported outcomes of laparoscopic Burch colposuspension versus the transobturator tape (TOT) midurethral sling procedure for treating stress urinary incontinence (SUI) in Egyptian women. METHODS: This was a rando...

Spatial Heterogeneity of Global Organic Matter Accumulation During the PETM

Abstract The Paleocene–Eocene Thermal Maximum (PETM) was an abrupt global warming event triggered by a massive release of isotopically light carbon. Rapid recovery from the PETM has been attributed to enhanced burial of organic matter (OM). However, the mechanisms and spatial dis...

A 14-day repeated dose oral toxicity assessment of the aqueous-ethanolic extract of Schouwia purpurea in female Wistar albino mice

Schouwia purpurea (Family: Brassicaceae) S. purpurea is a wild medicinal plant traditionally used for treating gastrointestinal, inflammatory, and infectious disorders in arid regions of North Africa. Despite its ethnomedicinal importance, little is known about its systemic safet...