Armed Forces Hospital

Genetic disorders associated with neurodevelopmental disorders in children in Saudi Arabia: A systematic review and meta-analysis

Objectives: High consanguinity in Saudi Arabia has shaped the genetic architecture of pediatric neurodevelopmental disorders (NDDs), potentially increasing autosomal recessive (AR) etiologies and the diagnostic yield of exome-based testing. This study aims to synthesize genetic d...

Lipid accumulation product (LAP): a key indicator for metabolic dysregulation and inflammatory status in obesity

The Lipid Accumulation Product (LAP) is recognized as an indicator of lipid-induced cellular stress. While its predictive value for conditions like diabetes, liver disease, and metabolic syndrome is established, its specific correlations with individual metabolic and hematologica...

Evaluating the Role of MIA3 Variant rs17465637 in Coronary Artery Disease: A Comprehensive Case–Control Analysis

Objectives: Coronary artery disease (CAD) remains a leading cause of morbidity and mortality worldwide, yet population-specific evidence regarding the contribution of MIA3 genetic variation in Middle Eastern populations remains limited. This study investigated the association of...

Vitamin D deficiency among adults screened for orthodontic treatment in Saudi Arabia: prevalence and implications for trial recruitment

Vitamin D deficiency remains highly prevalent in the Middle East and may influence both oral-health research planning and orthodontic trial feasibility. This study estimated vitamin D deficiency prevalence in adults screened for orthodontic treatment in Saudi Arabia and quantifie...