Aristotle University of Thessaloniki

High Bleeding Risk Patients Undergoing Percutaneous Coronary Intervention: How to Choose the Optimal Antithrombotic Therapy, Its Duration and the Right Stent; A Comprehensive Review of the Current Literature and Proposed Treatment Algorithms

High bleeding risk (HBR) patients represent a significant proportion of those who undergo percutaneous coronary interventions (PCI). The accurate diagnosis of the HBR population is essential because they suffer significantly higher rates of mortality and bleeding compared with no...

Assessing Behavioral and Environmental Facets of Obesity Unobtrusively Utilizing Digital Tools: Introducing the BETTER4U Indicators

ABSTRACT Understanding obesity involves evaluating numerous contributing factors. Collecting the necessary data for this can impose a significant burden on both research participants during clinical studies and real‐life deployments of digital tools aiding obesity management. The...

Treatment restrictions after acute stroke across nine European countries and their association with 90-day mortality: a post hoc analysis of the PRECIOUS randomised controlled trial

Background In patients with acute stroke, early withholding or withdrawal of life-sustaining therapies is associated with an increased risk of death. We used practice variation across nine European countries to assess whether this relation may be causal. Methods We performed a po...

Promoting Inclusion and SDGs in Museums Through Art

The present study refers to the case of a STEAM (Science, Technology, Engineering, Arts & Mathematics) educational program that was implemented with individuals with disabilities in a thematic technological museum in Greece. The educational program entitled From the Olive Press t...

Earth Surface Controlled Wavefields in Ground-Penetrating Radar Responses

Abstract Ground-penetrating radar (GPR) data are commonly collected with the transmitting and receiving antennas in close proximity. Small transmitter – receiver offsets mean the direct waves can dominate or even saturate the receiver, masking near-surface target responses and po...

A Hybrid Ultra-Wideband and Inertial Measurement Unit Sensor System Can Accurately Measure the Sprinting Performance in Young Male Soccer Players

Background: This study investigated the concurrent validity and agreement of a hybrid ultra-wideband (UWB) and inertial measurement unit (IMU) wearable sensor system (K-Power) against criterion photocell timing gates during a 30 m sprint test, while secondarily exploring associat...

Gravity Degree-Depth Relations for High-Order Disturbing Potential Gradients

Abstract The degree-depth relation links the spherical harmonic degree to an operational depth scale for gravity signals. Previous studies have primarily examined the degree-depth relation for the gravity anomaly, the vertical component of the gravitational vector, and the gravit...

Isolated Thyroid Metastasis from High-Grade Clear Cell Renal Cell Carcinoma After Radical Nephrectomy: A Case Report

Background and Clinical Significance: Thyroid metastasis from clear cell renal cell carcinoma (ccRCC) is uncommon and may occur after radical nephrectomy despite no evidence of residual or metastatic disease at that time. Diagnosis can be challenging because imaging and fine-need...

Testing a Prespecified Matrix Transcriptional Programme in Myeloid Cells from Proliferative Vitreoretinopathy Membranes: A Donor-Aware Computational Single-Cell Study

Whether myeloid cells in proliferative vitreoretinopathy (PVR) membranes directly transcribe a coherent extracellular matrix (ECM) programme remains uncertain. We tested a prespecified seven-gene programme in a discovery cohort (GSE294329; five PVR donors) and an independent epir...

Health-related interpretation of human biomonitoring results – new and updated human biomonitoring guidance values from PARC and HBM4EU

During the first three years of the Partnership for the Assessment of Risks from Chemicals (PARC), we derived health-based human biomonitoring guidance values (HBM-GVs) for 11 substances to enable the direct health-related interpretation of human biomonitoring (HBM) results. HBM-...

Spatial Overlap Between Wind Power Licensing Areas and Potential Grazing Lands in Greece: A National Screening Assessment

Wind energy expansion constitutes a central component of Greece’s energy transition. However, the spatial allocation of Wind Power Production Plants (WPPs) may coincide with potential grazing lands and Natura 2000 protected areas, creating potential land-use and conservation inte...

On the Use of Hybrid Models and Latin Hypercube Sampling to Develop a Chemically Defined Culture Medium Formulation for pDNA Production in E. coli

The demand for pharmaceutical-grade plasmid DNA (pDNA) is projected to outpace current manufacturing capacity due to the expanding clinical pipeline of Advanced Therapy Medicinal Products (ATMPs). While regulatory bodies (FDA, EMA) advise against complex media in an evolving regu...

Parental stress, coping, and depressive symptoms among parents of preterm infants hospitalised in a Greek neonatal intensive care unit: A cross-sectional study

Purpose To examine NICU-related parental stress, coping strategies, and depressive symptoms in a single-centre, cross-sectional study of parents of preterm infants in a tertiary NICU in Greece. Principal results Thirty-four parents from 18 families participated. NICU-related stre...

Expectations, emotional responses, and early experiences with a newly introduced autonomous metro

Rapid advances in automation are transforming transport systems worldwide, with autonomous technologies increasingly being deployed in public transport. This study examines public perceptions of a newly introduced autonomous metro system during its initial phase of operation in T...

EUPopLink Country report - Greece

This report examines the overlap of Populism and Euroscepticism at the party level in Greece from the 1980s to today. It provides a longitudinal description of populist parties and their political platforms. While early populism was primarily represented by PASOK, it later became...

Development and validation of a multi-tier diagnostic test on the water footprint concept

Purpose Conceptual understanding is essential for effective sustainability education, yet students often hold alternative conceptions about key environmental issues. The water footprint (WF), a multifaceted indicator of water use, is increasingly included in sustainability curric...

First Molecular Detection of Neobenedenia girellae (Monogenea: Capsalidae) in Farmed Greater Amberjack (Seriola dumerili) in Greece

In the present study, we report the first molecular detection and identification of the ectoparasitic monogenean Neobenedenia girellae in the farmed greater amberjack (Seriola dumerili) in Greece. This parasite is considered one of the most economically important ectoparasites af...

Intensive vs Standard Blood Pressure Lowering in People With and Without Chronic Kidney Disease

Importance There is uncertainty about the effects of intensive blood pressure (BP) lowering on risks of cardiovascular disease and kidney failure in patients with chronic kidney disease (CKD). Objective To assess the standardized effects of intensive BP lowering on cardiovascular...

A mathematical theory of redox biology

Abstract Redox biology is commonly described through functional labels, such as oxidant, reductant, antioxidant, signalling mediator or damage mediator. However, these labels do not define invariant molecular properties. A molecule may realize different functions depending on rea...

Candidozyma auris Prosthetic Joint Infection: A Case Report and Systematic Case-Based Literature Review of Osteoarticular Infections

Candidozyma auris, recently taxonomically reclassified, represents an emerging multidrug-resistant fungal pathogen that has evolved into a critical nosocomial and global public health threat. This organism exhibits a profound capacity for resilient biofilm formation on biotic and...