Antalya IVF

The Interstitial Homeostatic Early-Warning System: Rethinking Preventive Laboratory Testing

Preventive laboratory testing primarily identifies established metabolic abnormalities, organ dysfunction, or systemic inflammation. This Perspective proposes that some pathological processes may first produce detectable disturbances within the tissue interstitium before conventi...

Long-Term Major Adverse Kidney and Cardiovascular Events in Predialysis Chronic Kidney Disease: A Real-World Cohort Study

Background and Objectives: Long-term renal and cardiovascular outcomes represent major clinical burdens in predialysis chronic kidney disease (CKD). This study aimed to evaluate the long-term incidence of and clinical factors associated with major adverse kidney events (MAKEs) an...

Associations of Self‐Reported Bruxism With Clinical Parameters, Perceived Stress, and Temporomandibular Disorders in Dental Students

ABSTRACT Background Bruxism has been assessed using heterogeneous methods across studies. The Bruxism Screener provides a standardized approach, but clinical studies using this tool remain limited. Moreover, factors influencing self‐reported bruxism in individuals with clinical b...

Absorbable tacker fixation versus non-fixation in totally extraperitoneal inguinal hernia repair: a prospective randomized study on postoperative pain and quality of life

The role of mesh fixation in laparoscopic totally extraperitoneal (TEP) inguinal hernia repair remains controversial. While fixation may increase postoperative pain, concerns about recurrence in larger defects prevent its complete abandonment. This study aimed to compare absorbab...

Diagnostic performance of Alvarado versus Karaman scoring systems in acute appendicitis: A retrospective comparative study

Aims: Acute appendicitis (AA) is the most common cause of acute abdomen requiring surgical intervention. This study aimed to compare the diagnostic accuracy and consistency of the classic Alvarado score, which is widely used worldwide in the diagnosis of AA, with the more recentl...

Ability of the HALP Score to Predict Cardiac Implantable Electronic Device‐Related Complications

BACKGROUND: The hemoglobin, albumin, lymphocyte, and platelet score (HALP) is a recently defined score that indicates patients' inflammation and nutritional status. This score is associated with poor outcomes in cardiovascular diseases. We aimed to examine the relationship betwee...

Two new genera, Limnohalacarus and Soldanellonyx (Acari: Halacaridae) in freshwater halacarid mites with additional new records from Turkey

Durucan, Furkan (2020): Two new genera, Limnohalacarus and Soldanellonyx (Acari: Halacaridae) in freshwater halacarid mites with additional new records from Turkey. Persian Journal of Acarology 9 (1): 1-11, DOI: 10.22073/pja.v9i1.57733

Real-world outcomes of children with first relapsed acute lymphoblastic leukemia treated according to the ALL-IC REL 2016 guideline in Türkiye

Relapsed acute lymphoblastic leukemia (ALL) remains a major challenge in pediatric oncology, particularly where access to modern immunotherapies is limited. This national multicenter study evaluated real-world outcomes of children with first relapsed ALL treated according to the...

Clinical Outcomes in Initial Hirudotherapy versus Standard Treatment in Idiopathic Granulomatous Mastitis: A Comparative Cohort Study

Objective: Idiopathic granulomatous mastitis (IGM) is a chronic inflammatory disease characterized by a high risk of recurrence and fistula formation. Spontaneous remission has been reported in up to 50% of cases, particularly in mild forms, within 6-24 months without interventio...

Association of blood parameters and ratios with aseptic loosening after total knee arthroplasty

This study aimed to evaluate the association of blood parameters and ratios with knee prosthesis loosening in patients after knee arthroplasty. A total of 221 patient files having knee prosthesis attempting to our clinic between 2018 and 2022 were retrospectively examined. Patien...

Causal inference from a single treated state: a peer review of Lee et al. (2024) and the exchange that followed

Lee et al. (2024) report that state-level anti-transgender laws caused increases of 7–72% in past-year suicide attempts among transgender and non-binary (TGNB) young people. A Matters Arising (Cohn et al., 2026) showed that the paper’s largest estimates derive from a single treat...

Histopathological subtypes of gastric neuroendocrine cell hyperplasia: a cross-sectional association with hypergastrinemia and coexisting gastric lesions at index endoscopy

Gastric neuroendocrine cell hyperplasia (NECH) is a hypergastrinemia-driven spectrum of enterochromaffin-like cell proliferation that may precede or coexist with well-differentiated gastric neuroendocrine tumors (g-NETs). However, the clinical relevance of specific histologic pat...

Real-world outcomes of second-line therapy in advanced thymic carcinoma: a multicenter Turkish Oncology Group (TOG) study

Abstract Background Thymic carcinoma (TC) is a rare and aggressive malignancy with limited evidence guiding second-line treatment after prior systemic therapy. We evaluated real-world outcomes of second-line systemic therapy in a multicenter cohort. Methods Adults with unresectab...

Online-Initiated Contact and Child Sexual Abuse Severity: A Forensic Cross-Sectional Study

Background/Objectives: Digital technologies have created new pathways through which perpetrators can initiate contact with children, yet evidence directly comparing child sexual abuse (CSA) cases according to the mode of first contact between the victim and the perpetrator remain...

Magnetic Intramedullary Lengthening Nails for Complex Lower Extremity Reconstruction: Functional Outcomes, Bone Healing, and Complications

Background: Magnetically controlled intramedullary lengthening nails have become increasingly popular for lower extremity reconstruction because they reduce complications associated with external fixation and facilitate earlier rehabilitation. However, comprehensive data integrat...

Modes of Delivery Impact Maternal Oxidative Stress Biomarkers and Dynamic Thiol Disulphide Homeostasis: A Prospective Comparative Study

The objective of the present study was to examine oxidative stress markers in serum samples in women who had vaginal deliveries and those who had elective cesarean sections. The study included 35 women who had spontaneous vaginal deliveries and 23 women who underwent elective ces...

Changes in depression, anxiety, and affect following repetitive transcranial magnetic stimulation applied to the left dorsolateral prefrontal cortex: A quasi-experimental study

In recent years, repetitive transcranial magnetic stimulation (rTMS) has become an increasingly prominent neuromodulation approach in the treatment of Major Depressive Disorder (MDD). Treatment success in the literature is predominantly evaluated in terms of reductions in depress...

Blood Pressure and Angina-Related Health Status During Benidipine Therapy: A Multicenter Real-World Cohort Study

Background: Benidipine is a long-acting calcium channel blocker used for the treatment of hypertension and chronic coronary syndrome. Although it effectively lowers blood pressure (BP), the relationship between BP reduction and improvement in angina-related health status during b...

Impact of adjuvant endocrine therapy on disease-free survival in early triple-positive breast cancer: a multicenter retrospective cohort study of the Turkish oncology group

Triple-positive breast cancer (TPBC), characterized by concurrent ER, PR, and HER2 positivity, poses unique therapeutic challenges due to ER–HER2 crosstalk. The optimal adjuvant endocrine therapy in TPBC patients receiving anti-HER2 regimens remains poorly defined. This multicent...