Ankara Onkoloji Eğitim ve Araştırma Hastanesi

Consent architecture in biobanking: ethical attitudes and consent preferences among people with cancer and caregivers

Ethical and socially accountable biobanking depends on public trust and informed consent. Understanding how people with cancer and caregivers view biospecimen use is essential for designing consent models that respect autonomy and reflect cultural values. This study examined cons...

Rejection Sensitivity Among Adults with Comorbid Borderline Personality Disorder and Attention-Deficit/Hyperactivity Disorder

Background: Rejection sensitivity (RS)—anxious expectations of interpersonal rejection—is consistently elevated in borderline personality disorder (BPD), but evidence in attention-deficit/hyperactivity disorder (ADHD), particularly in adults, remains limited and mixed. We compare...

Serum CEA, CA 19 − 9, and FDG PET/CT SUVmax in relation to histological subtype and overall survival in stage IV lung cancer

This retrospective study investigated the association of serum carcinoembryonic antigen (CEA) and carbohydrate antigen 19 − 9 (CA 19 − 9) levels with 18 F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) findings, histological subtype, and overall...

Large Language Models Versus Multidisciplinary Tumor Board Decisions in Thyroid Cancer

ABSTRACT Objectives Large language models (LLMs) are increasingly proposed as clinical decision‐support tools; however, their agreement with real‐world multidisciplinary tumor board (MDT) decisions remains insufficiently investigated in thyroid oncology. To evaluate the concordan...

Real-world outcomes of second-line therapy in advanced thymic carcinoma: a multicenter Turkish Oncology Group (TOG) study

Abstract Background Thymic carcinoma (TC) is a rare and aggressive malignancy with limited evidence guiding second-line treatment after prior systemic therapy. We evaluated real-world outcomes of second-line systemic therapy in a multicenter cohort. Methods Adults with unresectab...

Comparison of Direct Oral Anticoagulants and Low-Molecular-Weight Heparins in Cancer Patients with Nonvalvular Atrial Fibrillation: Insights from a Single-Center Experience

BACKGROUND: Atrial fibrillation (AF) is frequently encountered in patients with cancer and poses challenges for anticoagulant management. The present study was conducted to compare clinical outcomes associated with direct oral anticoagulants (DOACs) and low-molecular-weight hepar...

Determinants and prognostic significance of reduced heart rate variability for mortality and functional outcome after acute ischemic stroke

Objective: The study aimed to determine the predictors of reduced heart rate variability (HRV) in patients with stroke and to examine its relationship with functional outcomes and all-cause mortality.Methods:The 24-h Holter electrocardiographic recordings of patients referred to...

The Effect of Aromatherapy on Fatigue and Sleep Quality in Intensive Care Nurses: A Randomised Placebo‐Controlled Trial

BACKGROUND: Intensive care nurses are at high risk of fatigue and sleep disturbances due to irregular shift patterns and high levels of occupational stress. Although aromatherapy is increasingly used as a holistic intervention, evidence regarding its effects on fatigue and sleep...

Integrated Prognostic Stratification After Perioperative FLOT in Gastric and Gastroesophageal Junction Adenocarcinoma: A Multicenter Real-World Study

Background/Objectives: Outcomes after perioperative FLOT for gastric and gastroesophageal junction adenocarcinoma remain variable, even among patients treated with curative intent. Although postoperative pathological findings are central to risk assessment, they do not fully capt...

Impact of adjuvant endocrine therapy on disease-free survival in early triple-positive breast cancer: a multicenter retrospective cohort study of the Turkish oncology group

Triple-positive breast cancer (TPBC), characterized by concurrent ER, PR, and HER2 positivity, poses unique therapeutic challenges due to ER–HER2 crosstalk. The optimal adjuvant endocrine therapy in TPBC patients receiving anti-HER2 regimens remains poorly defined. This multicent...