Anhui University of Traditional Chinese Medicine

Therapeutic Properties and Underlying Mechanisms of Traditional Chinese Medicine in Managing Rheumatoid Arthritis: An Integrative Review of Clinical and Molecular Findings

Traditional Chinese medicine (TCM) has a long-standing history in the treatment of rheumatoid arthritis (RA), known as "Bi Zheng," and offers a comprehensive therapeutic approach characterized by multi-target and multi-pathway mechanisms. Modern pharmacological research has demon...

Genome-wide characterization of the bZIP gene family in Rattus norvegicus and expression profiling analysis during brain development

The brown rat ( Rattus norvegicus ) serves as a cornerstone model organism in biomedical research, particularly for understanding physiological homeostasis and stress responses. The basic leucine zipper (bZIP) transcription factor family is a pivotal regulatory network involved i...

The effect of cochlear implantation in older adults: an umbrella review of systematic reviews and meta-analyses

INTRODUCTION: Age-related hearing loss is increasingly prevalent and impacts psychosocial wellbeing, cognitive health, and quality of life in older adults. While cochlear implants (CIs) are effective for severe-to-profound loss, their use in the elderly was historically cautious....

Interim Efficacy Analysis of Different Anticoagulation Regimens in Patients with Long-term Implantation of Inferior Vena Cava Filter

Abstract: To analyze the interim efficacy of different anticoagulation regimens for patients with long-term inferior vena cava filter (IVCF) implantation. From August 2021 to August 2024, a retrospective analysis of patients who underwent long-term IVCF implantation in multiple c...

Transport mechanism of type VI secretion system effectors based on Hcp, VgrG , and PAAR components

The type VI secretion system (T6SS) is a widespread contractile nanomachine in pathogenic bacteria that delivers diverse effectors directly into prokaryotic or eukaryotic target cells. These effectors confer competitive fitness advantages to attacker cells through multifaceted ta...

Climate-Driven Habitat Redistribution and Conservation Gaps of the Medicinal Fern Sceptridium ternatum in China

Climate change may redistribute understory medicinal plants, but national predictions are useful when model uncertainty and field constraints are explicit. We aimed to identify the current and future suitable habitat of Sceptridium ternatum and translate predictions into survey a...

Naoluotong granules inhibit necroptosis of neural cells and improve cerebral ischemia-reperfusion injury by regulating the RIP1/NIK/IKKα/NF-κB pathway.

BACKGROUND: Cerebral ischemia-reperfusion can cause structural changes in brain tissue and disrupt physiological functions. Naoluotong granules (NLT) exhibit significant neuroprotective effects on brain nerve cells and are widely utilized in treating cerebral ischemia-reperfusion...