Amrita Vishwa Vidyapeetham

Rationally Designed Phenyl- and Phenanthryl-Based Imidazole Hybrids for the Treatment of Breast Cancer—A Structure–Activity Relationship Study

A series of 11 compounds of phenyl–imidazole–pyrrole and 9 compounds of phenanthryl–imidazole–pyrrole were synthesized and evaluated against breast cancer cell lines differing in the expression of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth facto...

Comparative assessment of the global seaweed sector across developed, developing and least developed economies

Seaweed cultivation is one of the most sustainable marine production systems. The economic and nutritional importance of seaweed is increasing because of its protein, vitamin, essential amino acid, and various bioactive compounds. It is a nutrient-dense “blue food” that can be gr...

Graph hybrid neural network integration for enhanced diabetic retinopathy detection in retinal image

Diabetic retinopathy (DR) is a progressive microvascular complication of diabetes that affects the retina. This study presents a hybrid graph neural network (GNN) architecture that combines a graph isomorphism network (GIN) with GraphSAGE to improve performance and interpretabili...

A comparative study on the effects of clove oil, flaxseed oil, and almond oil as an additive on the lubricating characteristics of chemically modified used coconut oil

Abstract Lubrication is widely associated with contact surfaces having relative motion to decrease friction and wear. The majority of locally available lubricants have petroleum products as a base, which are toxic to the environment. The excess usage of petroleum products is also...

Unified Graph Convolutional Neural Network with PPMI-Informed Graphs and MuRIL Embeddings for Hate Speech Detection in Indian Code-Mix Text

The widespread use of social media has led to a rise in online bullying and abusive language. Huge amounts of content are created on social media daily, creating a challenge for platforms to manually detect and remove offensive posts, making automated detection systems essential....

Harnessing polymeric materials for applications in electric vehicle with sustainability contributions and prospects

The accelerated global shift to EVs is revolutionizing the field of materials science, thereby making polymeric materials indispensable to all subsystems in EVs. In this context, this review provides a critical analysis of the evolution, classification, and applications of polyme...

Beyond Doomsday: reading Von Foerster’s 1960 equation as a lesson in second-order cybernetics

Purpose This article revisits the 1960 “Doomsday” equation of Von Foerster, Mora and Amiot on the anniversary of its author’s birth. It asks what the equation’s now-evident empirical deviation teaches about prediction in social systems, and argues that the deviation is best read...

Aloe vera-PDMS blend thin films with combined triboelectric and polarization mechanisms for wearable energy harvesting

Abstract The development of flexible and sustainable self-powered electronics has driven interest in high-performance triboelectric nanogenerators (TENGs). In this work, Aloe vera (Av) juice was directly incorporated into a polydimethylsiloxane (PDMS) matrix (5–40 wt%) to enhance...

Order reduction of continuous-time interval systems using Padé-derived compact search bounds and mountain gazelle optimization

Model order reduction of interval systems is crucial for simplifying comprehension and designing reliable controllers while retaining uncertainty bounds. This study introduces a hybrid order-reduction framework that combines split-merge reformulation, Padé approximation, and the...

CFIR-guided formative implementation research to co-design a supervised toothbrushing programme through Anganwadi centres in Kerala, India

Dental caries remains a major public health concern among preschool children, driven by modifiable behaviours such as inadequate toothbrushing and poor oral health practices. Anganwadi Centres are community-based centres within India’s Integrated Child Development Services (ICDS)...

Sustainable hydrovoltaic power generation using surface functionalized MWCNT coated cotton strings

Hydrovoltaic energy harvesting systems provide an innovative technology for sustainable electricity generation by utilizing the immense untapped potential of water. Recently reported hydrovoltaic devices provideroutes for power generation using various carbon-based nanomaterials....

Spectral collocation approach for fractional order 2D viscous flow through expanding and contracting porous wall model

Abstract In this paper, 2-D viscous fluid flow in a expanding or contracting wall has been studied by incorporating fractional order in the Caputo sense. The governing two dimensional equations are transformed to a highly nonlinear fractional differential equations with associate...

Antifungal potential and ecological perspectives of selected seagrass species from tropical coastal meadows

Seagrasses have gathered increasing attention due to their multifaceted ecological roles. Apart from their ecological significance, seagrasses have exhibited potent antifungal properties, indicating potential for diverse applications. The antifungal efficacy of methanolic extract...

Clinicopathological profile and prognostic subgrouping of mantle cell lymphomas: A six-year retrospective study from a tertiary care center in Kerala

ABSTRACT Background: Mantle cell lymphoma (MCL) is a rare mature B-cell non-Hodgkin lymphoma that is known to exhibit heterogeneous biological behavior and variable clinical outcomes. Ki-67 proliferation index, blastoid morphology, and p53 expression are important prognostic mark...

From awareness to focus: using digital mindfulness and learning strategies to combat cognitive overload in the hybrid knowledge economy

Purpose This paper discusses digital mindfulness, a significant intervention to reduce the attention fatigue and cognitive overload in hybrid knowledge economy. Design/methodology/approach The study uses a conceptual approach focusing on mindfulness theory and the stages of chang...

A Novel Stable-Inverse Fractional-Order Predictive PID Control with Machine Learning-Based Performance Prediction for Non-Minimum Phase Systems

Non-minimum-phase behavior introduces an additional limitation in predictive process control because directly inverting a right-half-plane zero can result in an unstable controller. This study develops a Stable-Inverse Fractional-Order Predictive PID (SIFOPPID) controller for the...

Participatory rural appraisal for community-based water governance in rural India through a researcher’s positionality-informed approach

This present study offers the methodological intersections of Participatory Rural Appraisal (PRA) and non-native ethnography within the context of community-based water governance in Mohlai village, Chhattisgarh, India. It is an ethnographic study conducted in Mohlai village with...

Silencing with precision: In silico strategies for antisense oligonucleotide engineering

Therapeutics based on nucleic acids are emerging as a transformative drug class in the era of personalized medicine. They include antisense oligonucleotides (ASOs), aptamers, small interfering RNAs (siRNAs), small activating RNAs (saRNAs), microRNAs (miRNAs), and long non-coding...

Structural features, activity relationships, and synthetic strategies of indole-based derivatives as antitubercular agents targeting mycolic acid biosynthesis

Tuberculosis (TB) is a severe airborne infectious disease caused by Mycobacterium tuberculosis ( M. tb ), primarily impacting the lungs and other organs. Antimicrobial resistance in TB is an emerging problem that requires immediate treatment and management. It is difficult to cur...

Acoustic Emission Metrology for Real-Time TIG Welding Monitoring: Spectral Characterization and Interpretability via Explainable AI

Tungsten inert gas (TIG) welding of AA5083 aluminum alloy is sensitive to heat input and shielding conditions, which can lead to defects such as porosity and burn-through that compromise weld quality. Conventional non-destructive testing methods are generally performed after weld...