Al Azhar University

Application of in vitro digestion and dialysability procedure for bioavailability evaluation of toxic elements in green leafy vegetables: a realistic health risk assessment by Monte Carlo simulation

Green leafy vegetables (GLVs), which are vital and widely consumed worldwide, require monitoring for contaminants, including toxic elements (TEs). This study measured total concentrations (TC) and bioavailable concentrations (BC) of arsenic (As), cadmium (Cd), lead (Pb), chromium...

A closer insight into the molecular effect of canagliflozin on gentamicin–induced nephrotoxicity in rats: Attention to SIRT1/Nrf2/HO-1, p38 MAPK/NF-κB signaling pathways, and expression of miR-21 and miR-155.

OBJECTIVE: Nephrotoxicity is considered the most detrimental effect of gentamicin (GM). In this study, we investigated the potential effects for canagliflozin (CANA) to protect against GM-induced nephrotoxicity, besides the multiple molecular pathways underlying these effects. ME...