Al-Azhar University

The filtration performance of fabrics against particles of viral size: a systematic review

Wearing a mask is part of the comprehensive strategy to suppress transmission of the SARS-CoV-2 virus and respiratory tract infections. Despite available COVID-19 vaccines, wearing a mask has remained one of the simplest and most effective ways. There was, however, little data av...

Molecular characterization and spoilage potential of yeasts isolated from traditional Egyptian Karish cheese

Traditional soft cheeses are susceptible to microbial contamination, particularly when unsterilized flavoring additives are used during production or retail handling. This study aimed to quantify and molecularly characterize the yeast flora associated with spiced Karish cheese, a...

Efficacy and Safety of Baxdrostat for Patients With Uncontrolled or Resistant Hypertension: A Systematic Review and Meta-Analysis

We evaluated the efficacy and safety of baxdrostat in adults with uncontrolled or resistant hypertension. We searched PubMed, Scopus, Web of Science, and Cochrane CENTRAL from inception to January 2026. We included randomized controlled trials that involved hypertension patients...

Oral Co-supplementation with Pediococcus pentosaceus Probiotic and Enteric Polymeric Phycocyanin Nanoparticles Mitigates Aging-Related Biomarkers in Male Wistar Rats: A Preclinical Investigation

Abstract C-phycocyanin (C-PC) is a promising anti-aging nutraceutical due to its antioxidant and anti-inflammatory properties; however, its instability under acidic conditions limits its efficacy, necessitating advanced formulation strategies. This study evaluated the anti-aging...

Evaluation of the new Egyptian undergraduate medical program from the perspectives of faculty and institutional leadership: a nationwide, mixed-method study

Abstract Background In response to global calls for medical education reform, Egypt restructured its national undergraduate medical education program from a 6 + 1 model to a competency-based “5 + 2” model. This reformed program emphasizes early clinical exposure, integration of b...

Sustainable synthesis of Ag/UiO-66 composites using recycled silver for efficient adsorption of methylene blue and crystal violet

Abstract Synthetic dyes are persistent and toxic water pollutants that require efficient removal technologies, and metal–organic frameworks (MOFs) have emerged as promising adsorbents for this purpose. In this work, a defect-engineered zirconium-based UiO-66 framework was synthes...

Effect of diode laser on micro-tensile bond strength of hybrid ceramic restorations to dentin using one-step and two-step self-etch adhesives: in vitro study

Abstract Background This study aimed to evaluate the effect of diode laser irradiation on the micro-tensile bond strength (µTBS) of hybrid ceramic restorations bonded to dentin using one-step and two-step self-etch adhesives. Methods An in vitro study was conducted using 20 fresh...

Phytochemical profile and in vitro antimicrobial, antiviral, and anticancer activities of Echium angustifolium ethanolic extract

Echium angustifolium is traditionally valued for its therapeutic properties; yet comprehensive studies on its biological activities are limited. Aerial flowering parts were sequentially extracted with solvents of varying polarity. Extracts were analyzed for yield, phytochemical c...

A sensitive and green spectrofluorimetric method for determination of guanfacine hydrochloride based on NBD-Cl derivatization

A sensitive and environmentally friendly spectrofluorimetric method was developed for the determination of guanfacine in pharmaceutical formulations. The method is based on derivatization of guanfacine with 4-chloro-7-nitrobenzofurazan in alkaline medium to yield a highly fluores...

Evaluation of Moringa oleifera extract and metal-organic frameworks (MOFs) as therapeutic agents against chronic Toxoplasma gondii infection in mice

Abstract Toxoplasmosis, a zoonotic infection caused by the protozoan Toxoplasma gondii , remains a significant global health concern, with seroprevalence exceeding 60% in specific regions. Given the limitations of current therapies for chronic stages, this study investigated the...

Chemical desorption of methanol induced by hydrogen abstraction–addition cycles on cold grain surfaces

Abstract We report ultra-high vacuum experiments on the non-thermal desorption of methanol (CH3OH) from cold dust-grain analogues under hydrogen-atom bombardment. Monolayer methanol films on polycrystalline gold, compact amorphous solid water (ASW, 10 ML) and 13CO ice (2 ML) are...

Can Carica papaya Serve as an Adjunct to Semaglutide in Mitigating Diabetes-Induced Testicular Injury Through Modulation of Oxidative Stress, Inflammation, Apoptosis, and the miR-34c/miR-155–SIRT1/FOXO1 Axis? An Experimental and Chem-Bio-Informatics Study

Diabetes mellitus (DM) induces significant endocrine disruption and oxidative stress (OS) within the testes, resulting in impaired spermatogenesis, increased sperm abnormalities, and compromised reproductive function. This study aimed to evaluate the combined protective effects o...

Green synthesis of Ni-doped ZnO nanoparticles using Salvia hispanica and their antibacterial, anticancer and anti-virulence activities

An environmentally benign approach was employed to synthesize nickel-doped zinc oxide (Ni–ZnO) nanoparticles employing Salvia hispanica extract as a biologically derived reductant and capping material. Phytochemical profiling confirmed the abundance of phenolic and flavonoid comp...