Ahvaz Jundishapur University of Medical Sciences

Exosomes improved oxidative stress and apoptosis in BPA-induced nephrotoxicity in kidney cells through modulation of Nrf2/Keap1 signaling pathway

Bisphenol A (BPA) is an environmental toxicant known to induce nephrotoxicity primarily through oxidative stress–mediated inflammation and apoptosis. Mesenchymal stem cell-derived exosomes have recently emerged as promising cell-free therapeutic agents with antioxidant and anti-a...

The association between stress hyperglycemia ratio and adverse outcomes in patients with chronic kidney disease: a systematic review and meta-analysis

Chronic kidney disease (CKD) increases risks of cardiovascular events and mortality, so reliable biomarkers are needed to improve risk stratification. Stress hyperglycemia ratio (SHR), which adjusts acute glucose levels for chronic glycemia using glycated hemoglobin, has shown pr...

The effectiveness of clinical guideline on the caregiving performance of mothers with children with cystic fibrosis: A clinical trial study

Cystic fibrosis is an inherited disorder that causes severe damage to the lungs, digestive system, and other organs of the body. The aim of this study was to determine the effectiveness of clinical guidelines on the caregiving performance of mothers with children with cystic fibr...

The effect of the delivery mode on the total antioxidant activity, oxidative stress, and serum bilirubin level in G6PD-deficient male newborn infants

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a common condition worldwide that significantly increases the risk of neonatal hyperbilirubinemia and bilirubin encephalopathy. While some G6PD-deficient neonates exhibit hemolysis triggered by known oxidative exposures, such...

Acellular lung matrix scaffold coated by fibronectin enhances hepatic differentiation of adipose-derived mesenchymal stem cells

End-stage liver disease is a multifactorial disorder and leading cause of death.The development of effective tissue models has been a focus of research for treating liver disease.This study investigated the use of acellular lung matrix (ALM) and fibronectin (FN) to culture adipos...

Association between skeletal maturation and the developmental stages of the maxillary canine and mandibular second and third molars across different vertical facial patterns

Abstract Background Skeletal maturation and dental developmental stages are widely used indicators of biological growth in orthodontics. This study aimed to evaluate the association between skeletal maturation and the developmental stages of the maxillary canine (U3) and mandibul...

Brucella abortus RB51 vaccination: a comprehensive systematic review of safety, efficacy, and global field outcomes (1990–2025)

Brucella abortus strain RB51 is a live attenuated rough vaccine developed to overcome the serological interference of conventional smooth vaccines. Since replacing strain S19 in the United States (1996) and globally thereafter, RB51 has been promoted as a DIVA (Differentiating In...