Affiliated Hospital of North Sichuan Medical College

Evaluation of the safety and efficacy of 225Ac-PSMA-CY313 in metastatic castration-resistant prostate cancer: preliminary results

Abstract Objective Metastatic castration-resistant prostate cancer (mCRPC) remains associated with poor long-term outcomes, and survival under current treatment is modest. Prostate-specific membrane antigen (PSMA)-targeted alpha therapy using 225 Ac exhibits superior cytotoxicity...

MRI-based radiomic models of subchondral bone for predicting the occurrence of knee osteoarthritis

To extract the MRI-based radiomic features of subchondral bone, and establish multi-regional radiomic models and delta-radiomic models for predicting the 2-year risk of knee osteoarthritis (KOA). The data used in this study were obtained from the osteoarthritis initiative (OAI)....

Nasopharyngeal Carcinoma With Multiple Metastases Detected by Al 18 F-NOTA-FAPI-04 PET/CT

Nasopharyngeal carcinoma (NPC) is a prevalent epithelial malignancy. NPC tends to infiltrate locally early and typically involves regional nodes. Patients with terminal disease often develop distant metastases. We report a case of NPC with multiple metastases on 18 F-FAPI-04 PET/...

Factors associated with inpatient medical record data quality in hospital settings: a systematic review

Inpatient medical record data are an important source of information for clinical care, hospital management, clinical coding, and reimbursement. Poor-quality record data may lead to incomplete documentation, coding errors, inaccurate performance assessment, and distorted reimburs...

Integrative network toxicology and transcriptomic analysis identifies candidate molecular links between drinking-water disinfection by-products and prostate cancer

Disinfection by-products (DBPs) are ubiquitous contaminants generated during drinking-water disinfection and have been associated with adverse health outcomes. Although epidemiological and toxicological studies have linked long-term DBP exposure to urinary tract malignancies, the...

Preoperative enhanced CT lymph node parameters and postoperative pathology for predicting regional control failure after neck dissection for oral cancer

Background Regional control failure (RCF) after neck dissection (ND) remains a major determinant of poor survival in oral squamous cell carcinoma (OSCC). The objective of this research was to devise and confirm a combined predictive model incorporating preoperative contrast-enhan...

A machine learning model based on mPASS and imaging features for early assessment of clinically relevant outcomes in acute pancreatitis

To develop and validate a machine learning (ML) model based on the modified pancreatitis activity scoring system (mPASS) and imaging features for the early assessment of multiple clinically relevant outcomes in acute pancreatitis (AP). A retrospective cohort of 420 AP patients wa...