Aberystwyth University

Modeling the Subglacial Sediment System of the Finnish Lake District Ice Lobe During Deglaciation

Abstract. The systematic connection of glacial conditions in ice models with subglacial geomorphological observations has been limited by an inability to model subglacial sediment processes. The Finnish Lake District Ice Lobe (FLDIL) presents an opportunity to apply new model app...

Compressive Sensing for Reconstruction of Noise from an Aeroengine with Elliptic-Shaped Intake

Abstract Based on our prior theoretical model for elliptical mode detection, compressive sensing is introduced in this work to overcome the limitations of Nyquist-Shannon sampling. The key contribution is showing how to apply compressive sensing to an elliptic duct, which holds p...

Fingolimod overcomes cisplatin resistance in esophageal squamous cell carcinoma by targeting NUP54 to disrupt homologous recombination repair

Cisplatin resistance is a major obstacle in the treatment of esophageal squamous cell carcinoma (ESCC). To address this challenge, we screened a U.S. Food and Drug Administration (FDA)-approved drug library and identified fingolimod, an immunomodulatory agent, as a potent inhibit...