Yuji Marutani

Digital Soma: Friction Regulation Model and Agency Compression

Digital Soma is a theoretical and computational framework for examining a possible transition from AI-assisted human cognition toward AI-mediated regulation of human emotion, behavior, and the conditions of transformation at civilizational scale. This work develops a minimal sing...

Phase-Synchronized Dual-Target Modulation Rescues Long COVID In Silico: A Langevin Dynamics and Pontryagin Optimal Control Approach

Background: Long COVID (Post-Acute Sequelae of SARS-CoV-2, PASC) presents as a heterogeneous, treatment-resistant chronic syndrome. Conventional anti-inflammatory monotherapies frequently fail in clinical trials, exhibiting post-treatment rebound oscillations. We hypothesize that...

Phase-Synchronized Dual-Target Modulation Rescues Long COVID In Silico: A Langevin Dynamics and Pontryagin Optimal Control Approach

Background: Long COVID (Post-Acute Sequelae of SARS-CoV-2, PASC) presents as a heterogeneous, treatment-resistant chronic syndrome. Conventional anti-inflammatory monotherapies frequently fail in clinical trials, exhibiting post-treatment rebound oscillations. We hypothesize that...

Treatment Timing, Metabolic Modulation, and Bifurcation-Proximity Control in a Coupled Tumor–Immune–Drug Model

This record represents version 1.0.0 of the calibrated computational model. The calibrated drug-input amplitude is explicitly specified as I_amp = 0.45 to maintain synchronization between the computational implementation and the manuscript. The model remains in the subcritical re...

Treatment Timing, Metabolic Modulation, and Bifurcation-Proximity Control in a Coupled Tumor–Immune–Drug Model

This record represents version 1.0.0 of the calibrated computational model. The calibrated drug-input amplitude is explicitly specified as I_amp = 0.45 to maintain synchronization between the computational implementation and the manuscript. The model remains in the subcritical re...

Benchmarking Semantic Closure Across AI-Mediated Representation Transformations

As AI systems increasingly function as multimodal knowledge compilers, an unresolved question is whether high-order conceptual structure survives transformation across representational media. We introduce the Semantic Reconstruction Benchmark (SRB 1.0.0-canonical)...