Yixin Guo

Epitope-conditioned generation of T-cell receptor β-chain CDR3 candidates using a pre-trained transformer model

Prioritizing T-cell receptor (TCR) candidates for defined peptide-HLA targets is an important step in TCR-based immunotherapy development, but it still relies heavily on laborious and expensive experimental screening. Recent advancements in generative artificial intelligence have...

Prediction and Planning of Planting for Ecologically Suitable Areas of Cistanche deserticola Using MaxEnt

This study aimed to predict potentially suitable areas for Cistanche deserticola in China and to provide a scientific basis for its cultivation layout and production planning. Based on the MaxEnt algorithm and ArcGIS spatial analysis, two independent ecological niche models were...