Teck‐Peng Loh

β-CF3 Alkynones for Amine Conjugation under Aqueous Conditions

Abstract We report an aqueous conjugate addition of primary and secondary amines to β-CF3 alkynones under mild conditions without added metal catalysts or activating reagents. This protocol affords stable, CF3-containing enaminone conjugates in phosphate buffer and is applicable...

Dichloramine B: A Reagent for Regioselective Chloroalkoxylation of 3‐Aryloxindoles

A catalyst‐ and additive‐free strategy for the direct chloroalkoxylation of 3‐aryloxindoles has been developed using dichloramine B as a readily available electrophilic chlorinating reagent and alcohols as alkoxy nucleophiles. Notably, dichloramine B is converted to benzenesulfon...