Susan B. Powell

Natural anti–NMDAR1 autoantibodies are associated with lower risk for depression and PTSD symptoms after traumatic brain injury

Abstract Exposure to a traumatic brain injury (TBI) increases risk of developing psychiatric symptoms including depression, anxiety, and post‑traumatic stress disorder (PTSD). However, biological risk and resiliency factors that help explain the heterogeneity in outcomes are limi...

Maternal immune activation disrupts epigenomic and functional maturation of cortical excitatory neurons

Elevated levels of maternal pro-inflammatory cytokines following severe infection during gestation can disrupt offspring neural development and increase the risk of neurodevelopmental disorders. The viral mimetic Poly(I:C) reproduces the effects of gestational influenza exposure,...