S L Beck

CONVERGENT GENETIC ARCHITECTURE AND MOLECULAR PATHWAYS UNDERLYING COMORBIDITY BETWEEN OPIOID USE DISORDER AND OTHER PSYCHIATRIC DISORDERS

Background Opioid use disorder (OUD) is frequently comorbid with other neuropsychiatric disorders (NPDs), leading to worsening of both conditions. Despite decades of research, the molecular and genetic mechanisms underlying these comorbid conditions remain largely unclear. Method...

Robust inference and correlates from genetic associations with personality

Personality traits describe stable differences in how people think, feel and behave, and how they interact with and experience their social and physical environments1,2. Many questions remain unanswered about associations between DNA and personality traits, such as their robustne...