Rick G. Pleijhuis

Computational Approaches to Penicillin Allergy De-labelling: A Clinical Review

Abstract Penicillin allergy is recorded in roughly one in ten hospital patients, yet fewer than one in ten of those records reflects a real, clinically significant allergy. The mismatch matters: patients with a penicillin label receive more second-line and broader-spectrum antibi...

A proposed approach for involving general practice in integrated oncological decision-making for frail patients

As populations age, the number of older adults (≥70 years) diagnosed with cancer is increasing, now accounting for the majority of new cancer diagnoses and experiencing the highest treatment burden. Treatment decision-making in this population is often complex, as multimorbidity,...