Nikolaus Grigorieff

In extracto cryo-EM reveals eEF2 as a major hibernation factor on 60S and 80S particles

Abstract Cryogenic electron microscopy (cryo-EM) made impressive progress in resolving cellular macromolecules and their detailed interactions. Single-particle cryo-EM traditionally relies on purified macromolecules and lacks the complexity of cellular environments, whereas in si...