Menggang Yu

The Physical Constraints on the Functional Lifespan of the Heart: Membrane Lipid Peroxidation and the Lifetime Heartbeat Number

Background: The heart is a postmitotic organ that must sustain continuous mechanical activity for the entire lifespan of the organism. Each cardiac cycle generates oxidative damage to membrane lipids, and because cardiomyocytes do not divide, these lipids are not replaced by cell...

Cuteness as the Detection of Writability: A Theoretical Account of Relational Entry

Why do humans find some beings cute and not others? This paper argues that cuteness is the real-time detection of writability: a relational state in which another agent's interactive condition allows the observer's input. The argument proceeds in two steps. The first is deductive...

Sleep as Offline Maintenance: Why Loss of Consciousness Is Required for Low-Resistance Pathway Networks

Sleep is present across all sufficiently complex animal nervous systems, and its loss produces broad cognitive and physiological failure. Yet why sleep must exist, and why it must involve loss of consciousness, remains unexplained by current mechanistic descriptions. This paper d...

The Physical Laws of Life's Origin: An Independent Deduction Based on Neutralization Destiny, Memory Inertia, and Electrochemical Lift

Modern life sciences have accumulated immense knowledge about how carbon-based life works, yet the question of physical necessity—why carbon-based life must be the way it is rather than otherwise—has remained largely unaddressed. This paper proceeds from three known physical laws...

The Brain as the Densest Low-Resistance Pathway Network: Theorem Two from the Physical Derivation for Carbon-Based Life

This paper presents a physical derivation of the brain as the densest low-resistance pathway network that must emerge in any multicellular carbon-based system where charge flow is sustained by exogenous electrochemical potential gradients. Proceeding from the same physical princi...

A Physical Derivation of the Heart: The Geometrically Predetermined Dissipation Center in Multicellular Aggregates Theorem One from the Physical Derivation for Carbon-Based Life

This paper presents a physical derivation of the heart as the geometrically necessary dissipation center that must emerge in any dense multicellular aggregate under the constraints of electrochemical energy injection and the second law of thermodynamics. We demonstrate that when...

A Structural Breakpoint in the Diastolic-Systolic Interval Ratio at ~135 bpm: Prediction from a Physical Framework of Cardiac Inevitability and Verification Using Public Exercise ECG Data

Why must the heart pulsate? Why is its position anatomically central? Many coreobservations in cardiac physiology—from the necessity of pulsation to thearterial-venous topological differentiation—currently lack a unified explanationat the level of physical necessity. Here, we pro...

A Comprehensive Empirical Study of the Critical Point at N/Z = 1.55 in Heavy Nuclides: Six Independent Dimensions of Evidence

Whether a universal critical N/Z value governs the stability and decay modes of all heavy nuclides has remained unresolved. Using experimental data from the ENDF/B-VIII.0, NuDat 3.0, ENSDF, and AME2020 public databases, this paper identifies N/Z = 1.55 as a structural break point...

The Physical Essence of Decoction: From Molecular Extraction to Charge Topology Transfer

Traditional Chinese medicine decoction has long been viewed as a chemical extraction process—water decocting dissolves the active components of medicinal herbs, and molecules are considered the sole carriers of medicinal efficacy. This paper proposes a competing hypothesis: the c...

Two Maintenance Strategies for the Human Electrochemical System: The Physical Basis of Diagnostic and Therapeutic Concepts in Traditional Chinese Medicine

The human body is a body-wide electrochemical system: cell membranes serve as capacitive units, mitochondria as energy conversion engines, autonomic nerves as regulatory wiring, and the brain as the control center with the densest low-resistance pathways carved by the history of...