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ARTICLE 2. MEMORY THEORY: THE PHYSICS OF WATER MOLECULES

According to the Non-Information Theory of Life (NJT), living systems are described as supramolecular ensembles capable of maintaining their identity in the flow of matter and energy. The key mechanism for preserving identity is physical memory – the ability of the system to reco...

ARTICLE 8. MEMORY THEORY: ABIOGENESIS – HOW THE FIRST CELLS WERE CREATED

According to the Non-Information Theory of Life (NJT), life is defined as the ability of a supramolecular ensemble to maintain its identity in a continuous exchange of matter and energy. Previous works in the series described the physical mechanisms of recording (tetrasignatures...

ARTICLE 5. MEMORY THEORY: TRIANGLE OF LIFE — MEMORY, ENZYMES AND ENERGY

Previous papers in the series described the fundamental mechanisms of physical memory recording and storage, as well as their role in abiogenesis and enzyme evolution. However, the question of the role of energy in this system remained open. Existing theories of the origin of ene...

ARTICLE 2. MEMORY THEORY: THE PHYSICS OF WATER MOLECULES

According to the Non-Information Theory of Life (NJT), living systems are described as supramolecular ensembles capable of maintaining their identity in the flow of matter and energy. The key mechanism for preserving identity is physical memory – the ability of the system to reco...

Meta-regulator No.8. Neuro-vegetative system of tone and reactivity regulation

The neuro-autonomic meta-regulator is an integrative system that maintains a dynamic balance between the sympathetic (adrenergic) and parasympathetic (cholinergic) regions of the autonomic nervous system, determining the speed of response to external and internal stimuli, as well...

Meta-regulator No.5. Proton buffer: acid-base equilibrium maintenance system

The proton-buffer regulator is an integrative system that maintains the concentration of protons (pH) in all fluids of the body within a narrow physiological range. It is based on buffer systems (bicarbonate, protein, phosphate, hemoglobin), respiratory regulation (control of pCO...

Meta-regulator No1. Chrono: a system of circadian and ultradian synchronization of physiological processes

The chrono-regulator is a distributed network of molecular oscillators that provide periodic changes in the metabolic activity of cells, synchronized with the external illumination cycle. It is based on transcription-translational loops involving the CLOCK, BMAL1, PER, and CRY ge...

Meta-regulator No.4. Regenerative-niche: a system for maintaining tissue homeostasis through stem cells and their microenvironment

A regenerative-niche regulator is a distributed network of local microenvironments (niches) in which a pool of stem and progenitor cells is maintained, ensuring the renewal of body tissues throughout life. It is based on signaling pathways (Wnt, Notch, Shh, BMP, FGF), growth fact...