Joshua E. Elias

GPR35-positive mast cells are enriched in primary sclerosing cholangitis and show an enhanced secretory phenotype

OBJECTIVE: dependent mast cell biology relevant for cholangitis and biliary fibrosis. METHODS: knockdown were determined by DESeq2 and gene set enrichment analysis. Selected cytokines, TNFα and IL13, were measured by qRT-PCR and ELISA. Mast cell-cholangiocyte interaction was stud...