Jie‐Ping Wan

Base-Promoted Hydrophosphorylation of Enaminones for the Synthesis of Geminal Phosphoryl Amino Ketones

Abstract The direct hydrophosphorylation reaction of NH-enaminones has been achieved by simple base promotion with diaryl phosphine oxides as reaction partners. The synthesis of divergent β-phosphoryl-β-amino ketones has been allowed under mild heating (30 °C) in a green medium o...

Cascade In Situ Iodination and Elemental Copper-Mediated Reductive Coupling for the Synthesis of 3-Difluoroacetate-Functionalized Chromones

Abstract Reported in this paper is an I2/Cu-mediated method for the synthesis of 3-difluoroacetate-functionalized chromones via cascade reactions between o-hydroxyaryl enaminones and alkyl difluoroacetates. The product construction involves a key in situ iodination generating 3-i...

HFIP-Assisted Electrochemical Annulation of Enaminones with Phenols for the Selective Synthesis of 7-Aryloxy and 5-Hydroxy Benzofurans

Abstract The electrochemical annulation reactions between enaminones and phenol derivatives have been achieved for the selective synthesis of 7-aryloxy benzofurans and 5-hydroxy benzofurans. With an electron-donating group (EDG), such as alkoxy or amino-functionalized phenols as...