Ines Abdallah

Preventative Germline Gene Editing via Biomimetic Soft-Robotic Delivery Prior to Puberty

This concept paper presents a preventative, early-stage approach targeting reproductive stem cells (Spermatogonial Stem Cells/Oogonia) prior to puberty to mitigate monogenic neurodevelopmental traits. The framework integrates targeted lipid nanoparticles (LNPs) carrying base edit...