Devesh U. Kapoor

Box–Behnken design–based optimization of Imatinib mesylate PLGA nanoparticle-loaded gel for topical management of Dermatofibrosarcoma Protuberans

Dermatofibrosarcoma Protuberans (DFSP) is a rare, locally aggressive cutaneous sarcoma. Its development is related to the specific PDGFB-COL1A1 fusion gene, which leads to constitutive signaling through tyrosine kinase. While Imatinib Mesylate is known to be effective in targetin...

3D-printed nanoparticle-encapsulated alginate carriers for breast cancer modeling, diagnosis, and precision therapy

Breast cancer is the most prevalent cancer among women, with approximately 2.3 million new cases and 685,000 deaths reported annually. Projections indicate that the global burden will exceed 6 million cases by 2050, underscoring the necessity for innovative research models and th...