Ayşen Işık

Synthesis, in silico study and cytotoxic evaluation of new benzimidazole derivatives as potential aromatase inhibitors

AIMS: ) was designed, synthesized, and evaluated as potential aromatase inhibitors with anticancer activity. MATERIALS AND METHODS: ADMET profiling were performed for the selected compounds. RESULTS: values (2.40-2.64 µM), surpassing cisplatin, while maintaining favorable selecti...